NAD+ is everywhere in the longevity space right now, and there's still so much confusion about it. Is it a peptide? (It's not, it's a coenzyme.) Why does it start dropping in your early 30s? And why can't you just swallow it in a capsule and call it a day?

If you want to do this work with me, work with me one on one. I see women every week for peptides, nervous system, nutrition and longevity, and you can book a free 15 minute call with me here.

In this episode I break down what NAD+ actually does for your energy and repair, then I sit down with Nicholas Signore, co-founder of The Rhythm Line, on the day RHYTHM launched. Nick shares his story, from getting sober almost two years ago to meditation, breathwork and Joe Dispenza, and how buying an NMN supplement that had almost nothing in it led him and his cardiologist partner to build their own.

We get into all seven ingredients (NMN, Setria glutathione, CoQ10, PQQ, trans-resveratrol, vitamin D3 and black pepper extract), why delayed release capsules matter when stomach acid breaks down NMN and glutathione, their third party Eurofins results, and how NAD+ IVs, injections, patches and nasal sprays compare to a capsule.

My husband and I take RHYTHM, two capsules a day, and we both notice it in our energy. This episode is in partnership with The Rhythm Line.

I TALK ABOUT:

00:00 What NAD+ is, why it declines in your 30s, and why you can't just swallow it

02:29 The seven ingredients in RHYTHM

05:28 Why delayed release capsules matter

07:25 Third party testing, and why women's heart health is underserved

11:13 Meet Nick: almost two years sober, meditation and Joe Dispenza

18:29 Microdosing and the default mode network

20:02 Getting ripped off by an NMN supplement, and how RHYTHM started

24:37 Why these seven ingredients, and beadlets vs delayed release

30:34 The Eurofins results: 667 mg of NMN and no heavy metals

34:13 How NAD+ supports energy, recovery and repair as we age

38:31 CoQ10 and PQQ for the heart (and why they're in fertility formulas)

41:11 NAD+ IVs, injections, patches, nasal sprays or capsules

RESOURCES:

• RHYTHM by The Rhythm Line (on Amazon US)
• Work with me one on one
• Book a free 15 minute call with me
• The LongHer Life on Substack
• The LongHer Life Online Community
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice. Some links are affiliate links.

GLP-1s are peptides. The P literally stands for peptide. Your body makes its own GLP-1 after every single meal, and it's gone within a couple of minutes by design. The drugs are that same signal, engineered so it never goes away, and that one difference explains both how well they work and almost everything women struggle with on them.

In this episode I break it all down. What a peptide actually is, how peptide drugs are built, and what your own GLP-1 does in your body. Then how to raise your own GLP-1 with protein, soluble fiber, healthy fats, fermented foods, meal order and how fast you eat, with real meal ideas (and why fasting doesn't raise it the way people think).

Then I go drug by drug: semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), retatrutide, the new oral GLP-1 pill, and generic semaglutide here in Canada. We talk half-life and steady state, what the labels actually say about dosing, what microdosing really means, what's different for women (bone, muscle, fertility and hair loss), and what happens when you come off.

I start with a personal story too: I sliced my finger open this week, and how my meditation practice let me regulate my nervous system in the ER.

This is education, not medical advice. If you want to do this work with me, work with me one on one. I see women every week for peptides, nervous system, nutrition and longevity, and you can book a free 15 minute call with me here.

My free GLP-1 boosting recipe booklet for women is coming very soon. Subscribe to the podcast, my Substack, or follow me on Instagram so you hear when it drops.

I TALK ABOUT:

• 00:00 Slicing my finger, the ER, and regulating my nervous system in an emergency
• 08:50 Why my peptide content is moving off Instagram, and what's in this episode
• 10:10 What a peptide is, and how peptide drugs are built to last
• 17:34 Your own GLP-1: what it does, why it's gone in minutes, and food noise
• 26:30 Raising your own GLP-1: protein, fiber, fats, meal order, CGMs and meal ideas
• 44:54 Fasting and GLP-1
• 46:35 Half-life, steady state, and what happens when you stop
• 53:30 Semaglutide, tirzepatide, retatrutide, the new GLP-1 pill and generics in Canada
• 1:04:06 Dosing and microdosing
• 1:10:15 What's different for women: bone, muscle, fertility and hair
• 1:18:12 Coming off, side effects, and questions to ask yourself
• 1:22:09 Peptides in food, rhythm vs signal, and the close

RESOURCES:

• Work with me one on one
• Book a free 15 minute call with me
• The LongHer Life on Substack (where my peptide content lives now)
• The LongHer Life Online Community
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice.

This is my live masterclass, The Exhale, from September. A few hundred women showed up live, and it's one of my favourite classes I've ever taught, so I'm giving you the whole thing here.

We go deep on peptides, longevity and the nervous system, and why the mind and nervous system have to come first before the body work and the advanced tools. I share my own postpartum anxiety story, the pattern I keep seeing in women, and why we can't out-peptide a dysregulated nervous system. Then I break down how cortisol shuts down growth hormone peptides, undoes gut peptides like BPC-157 and KPV, overrides sleep peptides, and why GLP-1s without protein, strength training and nervous system work put your muscle and bones at risk.

A note before you press play: about 18 minutes in there's a 12 minute guided future self activation, eyes closed. If you're driving, please don't close your eyes. Just listen, and come back to it when you can sit or lie down.

It ends with a full live Q&A: Retatrutide and microdosing, protein hacks and powders, MOTS-c and SS-31, creatine, BPC-157 and TB-500 for inflammation, glutathione, fasting, Kisspeptin before IVF, and labs.

If you want to do this work with me, work with me one on one. My three month program is open, I also do one off consultations, and you can book a free 15 minute call.

I TALK ABOUT:

• 00:00 Before you listen (and a note if you're driving)
• 03:21 Welcome to The Exhale
• 05:17 My postpartum anxiety story
• 09:13 Why nothing is sticking yet
• 16:18 Getting ready for the activation
• 17:55 Guided future self activation (12 min, eyes closed)
• 31:31 Coming back, and what came through
• 36:55 Fight or flight, rest and digest, and your HRV
• 39:32 Peptides and cortisol: growth hormone, gut health and sleep
• 48:09 GLP-1s, muscle, bone, and protein with peptides
• 57:18 Q&A: Retatrutide, protein, MOTS-c, creatine, BPC-157, Kisspeptin and labs
• 1:24:11 Becoming her, and the close

RESOURCES:

• Work with me: The Spark (my 12 week one on one program), a 60 minute consult, or a free 15 minute call
• The LongHer Life Longevity Community
• The LongHer Life on Substack
• Function Health, about $25 off with my link
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice. Some links are affiliate links.

Part one was how to look like yourself again. Part two was how to feel like yourself again. Part three is who you actually are, and it's the one that decides whether any of it sticks.

I open with something heavy from this week: I can't talk about peptides on Instagram anymore. I had to archive about 20 posts, my TikTok was deleted, and I've been blocked from DMs for three days. So I talk about building on borrowed land, and where I can still speak freely.

Then the three women I meet over and over. The one who knows exactly what to do and still hasn't started. The one who changes for a few weeks and then life creeps in. And the one who's waiting to feel ready. I go into why willpower runs out, why it's cyclical and tied to your hormones, and the five days I took completely off this month while my HRV sat in the 80s.

Then what actually builds it: deciding who she is out loud instead of setting a goal, one decision a day that she would make, changing the inputs instead of the intentions, and refusing to do it alone. Plus the question I asked a client this week that stopped her cold: what does it cost you to feel like this for another year?

This is for education, not medical advice. If you want to do this work with me, The Spark is open, and there are three spots left. One on one, 12 weeks, future self activations plus labs, nutrition, protocols and peptides.

Join The LongHer Life Longevity Community for women-specific guidance on peptides, hormones, longevity and soul.

LISTEN TO THE FULL SERIES
Part 1, how to look like yourself again: https://biohackingbrittany.com/blogs/podcast/how-to-look-like-yourself-again
Part 2, how to feel like yourself again: https://biohackingbrittany.com/blogs/podcast/how-to-feel-like-yourself-again

TIMESTAMPS
00:00 Welcome back, and why I can't talk about peptides on Instagram
03:24 Building on borrowed land, and why email matters
05:59 Part 3 of 3: look, feel, and now be
06:56 The woman who knows exactly what to do
08:42 The woman who changes for a few weeks
09:57 Willpower is cyclical, and your hormones run it
11:11 The five days I took off, and what my HRV did
12:51 The woman who is waiting to feel ready
15:30 Decide who she is, out loud
17:06 One decision a day that she would make
22:30 Change the inputs, and stop doing it alone
25:12 The Spark, three spots left

Instagram and TikTok @biohackingbrittany
Shop everything I use at biohackingbrittany.com

This episode is for educational purposes only and is not medical advice.

Today is how to FEEL like yourself again, and better, because you can get the body and still not feel like you.

I start with the sentence I hear on every call: "I just don't feel like myself." Then the three ways it actually shows up. Feeling flat with no spark, even when life looks good on paper. Tired but wired, snapping over nothing, awake at 3 AM. And numb, living in your head, disconnected from your own body.

Then the solutions. Breath and long exhales, heart coherence at about six breaths a minute, and what your HRV and resting heart rate are really telling you. The labs I want you to look at, including a four point cortisol test and blood work through Function Health. And the deepest one, the future self activation I do every morning, plus the alignment questions that decide whether any of it sticks.

If you want to do this work with me, The Spark is open. One on one, three months, activations plus labs, nutrition, protocols and peptides. There are 8 spots and application calls are 15 minutes.

I TALK ABOUT:

00:00 Welcome back, and what part 2 is

01:44 What women mean by "I don't feel like myself"

03:08 The Exhale replay, and The Spark

05:00 Feeling flat, with no spark

07:36 What flat looks like on your labs

09:04 Tired but wired, and the snapping

10:05 The cortisol curve and the 3 AM wake up

14:37 Numb and out of your body

19:15 Breath, long exhales and regulating daily

21:38 Heart coherence, and what your HRV is telling you

26:41 Labs, a 4 point cortisol test and Function Health

31:24 The future self activation, and the alignment questions

RESOURCES:

• The Spark, my one on one program, 8 spots
• Function Health, about $25 off with my link
• The LongHer Life Longevity Community
• Part 1: How to Look Like Yourself Again, and Better
• The Exhale, my free masterclass replay, up until Sunday night

Part three drops tomorrow: BE like yourself again.

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice.

I don't want you chasing the woman you were two years ago or before kids. I want you stepping into the woman you're becoming. This is part one of a three part series on how to look like yourself again, and better.

We get honest about weight and body composition: why lighter doesn't always mean better, why so many women are trading fat for frailty, and why a GLP-1 plateau usually isn't a dose problem. Across published trials of semaglutide and tirzepatide, lean mass makes up 25 to 39% of the weight lost, and muscle is the tissue that keeps your metabolism going.

Then I give you my three practical fixes: eat enough protein (one gram per pound of ideal body weight, front loaded in the morning), lift heavy with progressive overload, and stop measuring the wrong thing. I share how I weigh myself around my cycle, why I recommend a DEXA scan once or twice a year, my weekly training split, and the formula I use with every client: regulate your nervous system, build the foundation, then add peptides.

If you want me to build this with you, The Spark, my 12 week one on one program, is open with only eight spots.

I TALK ABOUT:

• 05:53 A three part series, and where my peptide content lives now
• 07:40 Why "and better": the future you, not the old you
• 11:43 Lighter doesn't always mean better
• 16:28 Trading fat for frailty
• 17:45 The GLP-1 plateau and muscle loss
• 21:34 Eating healthy and still losing muscle
• 24:31 Fix 1: eat enough protein (plus weighing and DEXA scans)
• 34:53 Fix 2: lift heavy and progressive overload
• 39:05 Fix 3: stop measuring the wrong thing
• 40:20 The formula: foundations, nervous system, then peptides
• 44:24 The Exhale, The Spark and a sign from the universe

RESOURCES:

• The Spark, my 12 week one on one program. Book a free 15 minute application call.
• The Exhale, my free masterclass. The replay is up until Sunday, September 27.
• The LongHer Life Longevity Community
• The LongHer Life on Substack, where my peptide content lives now
• Booty by Bret app (Bret Contreras) for tracking progressive overload

CONNECT:

• Instagram
• Website

Part two drops tomorrow: the thing underneath how you look.

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice.

Welcome to The LongHer Life, formerly Biohacking with Brittany. To kick off this new era, I'm not giving you a list of supplements. I'm giving you me. These are 10 things you probably don't know about me, and some of them I've never said on the mic before.

I share why I outgrew Biohacking with Brittany, and I read you the letter I wrote to my old self to close that chapter. Then we go deep: growing up in South Africa and moving to Canada at 7, my parents' divorce and caring for them as a teenager, growing up very Christian and where I stand with faith and spirituality now, my breech baby and traumatic birth, and the postpartum anxiety and intrusive thoughts I didn't recognize until I came out of them.

I also open up about the hardest season of my marriage, how I pick up on energy, the signs I keep getting that I'm going to have twins, why I thought I'd never work one on one again, and what it's like being a visionary who still has mom guilt.

If you want to work with me, The Spark, my new 12 week one on one program, is open now. Early bird pricing and the first edition founder's box end September 27.

I TALK ABOUT:

00:00 Welcome to The LongHer Life, and why I changed the name

08:00 The letter I wrote to my old self

11:00 I'm South African

14:20 My parents' divorce

19:20 Growing up Christian, and where I stand now

24:40 My breech baby and traumatic birth

29:00 Postpartum anxiety I didn't know I had

36:00 The hardest season of our marriage

40:40 I pick up on energy

47:00 The signs I'm having twins

56:20 Why I opened my practice again: The Spark

1:07:00 I'm a visionary, and I still have mom guilt

RESOURCES:

• The Spark, my 12 week one on one program
• The Exhale, my free masterclass (everyone who signs up gets the replay free)
• The LongHer Life Longevity Community
• My Birth Story episode (2024)
• How to Have a Gentle C-Section
• Dr. Joe Dispenza's books and meditations
• The Body Keeps the Score by Bessel van der Kolk

CONNECT:

Instagram | Website

This episode is for education and connection only and is not medical or mental health advice. If you're struggling with postpartum anxiety or birth trauma, please reach out to your provider or someone you trust.