NAD+ is everywhere in the longevity space right now, and there's still so much confusion about it. Is it a peptide? (It's not, it's a coenzyme.) Why does it start dropping in your early 30s? And why can't you just swallow it in a capsule and call it a day?

If you want to do this work with me, work with me one on one. I see women every week for peptides, nervous system, nutrition and longevity, and you can book a free 15 minute call with me here.

In this episode I break down what NAD+ actually does for your energy and repair, then I sit down with Nicholas Signore, co-founder of The Rhythm Line, on the day RHYTHM launched. Nick shares his story, from getting sober almost two years ago to meditation, breathwork and Joe Dispenza, and how buying an NMN supplement that had almost nothing in it led him and his cardiologist partner to build their own.

We get into all seven ingredients (NMN, Setria glutathione, CoQ10, PQQ, trans-resveratrol, vitamin D3 and black pepper extract), why delayed release capsules matter when stomach acid breaks down NMN and glutathione, their third party Eurofins results, and how NAD+ IVs, injections, patches and nasal sprays compare to a capsule.

My husband and I take RHYTHM, two capsules a day, and we both notice it in our energy. This episode is in partnership with The Rhythm Line.

I TALK ABOUT:

00:00 What NAD+ is, why it declines in your 30s, and why you can't just swallow it

02:29 The seven ingredients in RHYTHM

05:28 Why delayed release capsules matter

07:25 Third party testing, and why women's heart health is underserved

11:13 Meet Nick: almost two years sober, meditation and Joe Dispenza

18:29 Microdosing and the default mode network

20:02 Getting ripped off by an NMN supplement, and how RHYTHM started

24:37 Why these seven ingredients, and beadlets vs delayed release

30:34 The Eurofins results: 667 mg of NMN and no heavy metals

34:13 How NAD+ supports energy, recovery and repair as we age

38:31 CoQ10 and PQQ for the heart (and why they're in fertility formulas)

41:11 NAD+ IVs, injections, patches, nasal sprays or capsules

RESOURCES:

• RHYTHM by The Rhythm Line (on Amazon US)
• Work with me one on one
• Book a free 15 minute call with me
• The LongHer Life on Substack
• The LongHer Life Online Community
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice. Some links are affiliate links.

GLP-1s are peptides. The P literally stands for peptide. Your body makes its own GLP-1 after every single meal, and it's gone within a couple of minutes by design. The drugs are that same signal, engineered so it never goes away, and that one difference explains both how well they work and almost everything women struggle with on them.

In this episode I break it all down. What a peptide actually is, how peptide drugs are built, and what your own GLP-1 does in your body. Then how to raise your own GLP-1 with protein, soluble fiber, healthy fats, fermented foods, meal order and how fast you eat, with real meal ideas (and why fasting doesn't raise it the way people think).

Then I go drug by drug: semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), retatrutide, the new oral GLP-1 pill, and generic semaglutide here in Canada. We talk half-life and steady state, what the labels actually say about dosing, what microdosing really means, what's different for women (bone, muscle, fertility and hair loss), and what happens when you come off.

I start with a personal story too: I sliced my finger open this week, and how my meditation practice let me regulate my nervous system in the ER.

This is education, not medical advice. If you want to do this work with me, work with me one on one. I see women every week for peptides, nervous system, nutrition and longevity, and you can book a free 15 minute call with me here.

My free GLP-1 boosting recipe booklet for women is coming very soon. Subscribe to the podcast, my Substack, or follow me on Instagram so you hear when it drops.

I TALK ABOUT:

• 00:00 Slicing my finger, the ER, and regulating my nervous system in an emergency
• 08:50 Why my peptide content is moving off Instagram, and what's in this episode
• 10:10 What a peptide is, and how peptide drugs are built to last
• 17:34 Your own GLP-1: what it does, why it's gone in minutes, and food noise
• 26:30 Raising your own GLP-1: protein, fiber, fats, meal order, CGMs and meal ideas
• 44:54 Fasting and GLP-1
• 46:35 Half-life, steady state, and what happens when you stop
• 53:30 Semaglutide, tirzepatide, retatrutide, the new GLP-1 pill and generics in Canada
• 1:04:06 Dosing and microdosing
• 1:10:15 What's different for women: bone, muscle, fertility and hair
• 1:18:12 Coming off, side effects, and questions to ask yourself
• 1:22:09 Peptides in food, rhythm vs signal, and the close

RESOURCES:

• Work with me one on one
• Book a free 15 minute call with me
• The LongHer Life on Substack (where my peptide content lives now)
• The LongHer Life Online Community
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice.

This is my live masterclass, The Exhale, from September. A few hundred women showed up live, and it's one of my favourite classes I've ever taught, so I'm giving you the whole thing here.

We go deep on peptides, longevity and the nervous system, and why the mind and nervous system have to come first before the body work and the advanced tools. I share my own postpartum anxiety story, the pattern I keep seeing in women, and why we can't out-peptide a dysregulated nervous system. Then I break down how cortisol shuts down growth hormone peptides, undoes gut peptides like BPC-157 and KPV, overrides sleep peptides, and why GLP-1s without protein, strength training and nervous system work put your muscle and bones at risk.

A note before you press play: about 18 minutes in there's a 12 minute guided future self activation, eyes closed. If you're driving, please don't close your eyes. Just listen, and come back to it when you can sit or lie down.

It ends with a full live Q&A: Retatrutide and microdosing, protein hacks and powders, MOTS-c and SS-31, creatine, BPC-157 and TB-500 for inflammation, glutathione, fasting, Kisspeptin before IVF, and labs.

If you want to do this work with me, work with me one on one. My three month program is open, I also do one off consultations, and you can book a free 15 minute call.

I TALK ABOUT:

• 00:00 Before you listen (and a note if you're driving)
• 03:21 Welcome to The Exhale
• 05:17 My postpartum anxiety story
• 09:13 Why nothing is sticking yet
• 16:18 Getting ready for the activation
• 17:55 Guided future self activation (12 min, eyes closed)
• 31:31 Coming back, and what came through
• 36:55 Fight or flight, rest and digest, and your HRV
• 39:32 Peptides and cortisol: growth hormone, gut health and sleep
• 48:09 GLP-1s, muscle, bone, and protein with peptides
• 57:18 Q&A: Retatrutide, protein, MOTS-c, creatine, BPC-157, Kisspeptin and labs
• 1:24:11 Becoming her, and the close

RESOURCES:

• Work with me: The Spark (my 12 week one on one program), a 60 minute consult, or a free 15 minute call
• The LongHer Life Longevity Community
• The LongHer Life on Substack
• Function Health, about $25 off with my link
• Instagram @biohackingbrittany

The LongHer Life, formerly Biohacking with Brittany, is the podcast for women who want to live longer and better, from hormones and peptides to meditation and energy.

This episode is for education only and isn't medical advice. Some links are affiliate links.