We all know “the dose makes the poison;” we feature the saying in our professional associations, our merch and our inside jokes. What if that is actually not what Paracelsus said, and what does this 16th century physician and his experience as a healthcare provider practicing during the information explosion brought on by the printing press have to teach medical toxicologists living through the leading edge of the AI information revolution? This talk hopes to teach the listener a little bit more about the alchemist who has been claimed as a founder of toxicology and discuss how his approach to his era’s information deluge can teach us to face the fire hydrant of content in 2026.

This talk draws lessons about drug policy from the history of what Professor Herzberg calls “white markets,” i.e., legal psychoactive pharmaceuticals. America is famous for its drug wars, but from Bayer’s Heroin to Purdue’s OxyContin, white markets have always been far larger, and while they have caused three major public health catastrophes, they have also been a site of policy creativity that can serve as a model for maximizing the benefit, while reducing the harms, of these desirable but dangerous products.

Mercury has been used since before recorded history as a medicine, cosmetic, and poison. In this episode, we explore the liquid metal’s functions and forms in consumer products, from ancient alchemical potions to modern skin-whitening soaps.

If you were to make a list of the people who have most shaped the world as we know it, Thomas Midgley, Jr. probably wouldn’t crack the top 50. Yet his influence has directly and indirectly touched the lives of billions across the last century and indeed continues to be felt to this day. Listen in to hear about the man who was responsible for developing not one but TWO of history’s worst toxins.

Edgar Allan Poe built a legacy on poems and short stories that delved into the mysterious and the macabre--but the events surrounding his own death remain disturbingly unclear. Found confused and disoriented on Election Day in 1849, he died days later without an autopsy or explanation. This talk examines Poe's final illness and the toxicological theories that may have been the cause.

Watching fireflies on a summer evening is one of the joys of the season. However, a fireflies light harbors a secret, and that secret can kill.

Conspiracy theory….or conspiracy fact? MK Ultra was one of the most controversial government programs that engaged in mind blowing atrocities. Let’s go down the rabbit hole together and explore what is known about the history of this program…and perhaps consider if aspects of it may still exist today!

Dr. Robert Buchanan’s murder trial captivated the public with its shocking details and gruesome display. Take a deep dive into the tragic story of this physician, where, not one, but two innocent lives were caught in the wake of one man’s pride.