**A 92% Reduction in Suicidal Thoughts: The Mental Health Impact of Hormone Replacement Therapy**

Could hormone replacement therapy play a much greater role in women's mental health than previously recognized?

In this episode of *The Longevity Protocol — Longevity Brief*, Dr. John Robinson and Dr. Cristina Bosch explore a compelling 2026 study published in *BJPsych International* involving 957 women undergoing menopause hormone therapy. Researchers reported a remarkable 92% reduction in suicidal ideation scores among women initially experiencing suicidal thoughts, alongside approximately 46% improvements in depressive symptoms.

Discover how estrogen, progesterone, and testosterone influence brain chemistry, emotional resilience, motivation, and psychological well-being—and why perimenopause may be one of the most overlooked periods of vulnerability in women's mental health.

The doctors discuss what these findings mean for comprehensive menopause care and why emotional well-being is essential to **Experienced Longevity**.

Dr. Krista Zelizney, PT, DPT WOMEN'S PELVIC HEALTH & ORTHOPEDIC REHABILITATION Dr. Zelizney earned her bachelor's degree in Exercise Science from the University of Mississippi and her Doctor of Physical Therapy from Florida International University. Her training includes pelvic rehabilitation through Herman & Wallace and pregnancy/postpartum corrective exercise. Dr. Jake Lape, PT, DPT, CSCS MEN'S PELVIC HEALTH, STRENGTH & SPORTS PERFORMANCE Dr. Lape earned his bachelor's degree in Exercise Science from the University of Mississippi and his Doctor of Physical Therapy from the University of Mississippi Medical Center. He is a Certified Strength and Conditioning Specialist with experience in orthopedics, sports rehabilitation, dry needling, and men's pelvic health.

Why Strength May Be One of the Most Important Predictors of How Well We Age

What if one of the most important organs for longevity isn't your heart or brain—but your muscle? Dr. John A. Robinson and Dr. Cristina Romero-Bosch reveal why skeletal muscle is far more than strength and appearance. From metabolic health and myokines to sarcopenia, protein, creatine, and resistance training, discover how preserving muscle may protect your independence, vitality, and quality of life as you age. Because longevity isn't simply about living longer. It's about remaining capable of living fully.