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Quinn Stillson MD: Longevity Medicine, Performance & Peptides

Quinn Stillson MD: Longevity Medicine, Performance & Peptides

Di: Quinn Stillson MD
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Quinn Stillson, MD, is a physician and strength coach. Each episode takes one question and works through the research: Does BPC-157 actually help injuries heal? How much muscle do GH peptides build, and do you keep it? Is retatrutide the right GLP-1 for you? Which supplements are worth taking, and which aren’t? You’ll get the mechanisms, the human data, the risks and an honest read on how strong the evidence is, including when the answer is “we don’t know yet.” Topics include peptides (BPC-157, TB-500, GHK-Cu, MOTS-c, Semax and more), GLP-1s like semaglutide, tirzepatide and retatrutide, testosterone, supplements, longevity testing and training for healthspan. Episodes are the audio versions of videos from the Quinn Stillson MD YouTube channel. When an episode refers to charts or study graphics, you’ll find them in the video. Free peptide guide and newsletter: quinnstillsonmd.com This podcast is for educational purposes only and is not medical advice. Talk with your physician before starting, stopping or changing any medication, peptide or supplement. Some compounds discussed are not FDA-approved.Copyright 2026 Quinn Stillson MD: Longevity Medicine, Performance & Peptides Disturbo fisico e malattia Esercizio e fitness Fitness, dieta e nutrizione Igiene e vita sana
  • Do Peptides Cause Cancer? BPC-157, TB-500, CJC-1295 & More
    Sep 5 2026
    "Do peptides cause cancer?" is one of the most common questions about BPC-157, TB-500, and the GH peptides—and it's also the most misunderstood. You're normally given one of two answers: yes, be terrified, or no, don't worry about it. Neither is right, because this was never a yes-or-no question. Cancer doesn't work that way—and once you understand how it actually does work, the question reshapes into something far more useful for deciding how to use these compounds. In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the complete framework: the three stages of cancer development, exactly which peptides act at each stage and how, actual estimated risk numbers for every peptide on the list, and what you should do differently because of it. Every peptide is placed against real-world comparators—obesity, alcohol, sedentary time, acromegaly, EPO, and organ transplant immunosuppression—so you know what "increased cancer risk" actually means in practice. In this video, you'll learn: What it actually means for something to "cause" cancer—initiation, promotion, and progression Why ~60% of men over 79 already have prostate cancer—and why that isn't as scary as it sounds Why no peptide can INITIATE cancer (and the one contaminant that can) Which peptides may actually LOWER your cancer risk (GLP-1s, Thymosin Alpha-1, MOTS-c, Epitalon, GHK-Cu) Melanotan I vs II: the human data, the case reports, and the UV confounder nobody mentions GH peptides: why the feedback system matters, and why IGF-1 LR3 and PEG-MGF are different Follistatin's two-faced relationship with cancer—promoter or suppressor? BPC-157: does it promote angiogenesis or just modulate it? Evaluating the anti-tumor claim TB-4/TB-500: the most concerning peptide on the list, and exactly why Arsenic in research-use-only vials—the Belgian study that found 10x the injectable limit Why "if peptides caused cancer, wouldn't we know by now?" is wrong—the Xeljanz lesson Estimated risk ranges for EVERY peptide, compared to obesity, alcohol, and smoking The four things that actually reduce your risk: screening, sourcing, dosing, and cycling Best for: – Anyone using BPC-157, TB-500, CJC-1295, Ipamorelin, IGF-1 LR3, or Melanotan – People who've heard peptides cause cancer and want the actual evidence – Anyone with a personal or family history of cancer considering peptides – Biohackers and clinicians who want mechanisms and numbers, not fear or dismissal – Anyone deciding whether the risk-benefit of a specific peptide is worth it Timestamps 00:00 Do Peptides Cause Cancer? Why You Need a New Framework 01:40 What "Causing" Cancer ACTUALLY Means (The 3 Stages) 03:22 Stage 1 - Initiation & DNA Damage 04:48 Can Peptides Damage Your DNA and INITIATE a Cancer? 06:09 Stage 2 - Promotion (And Why You Probably Already Have Cancer Cells) 10:17 Stage 3 - Progression & The Angiogenic Switch 13:37 Can Peptides PROGRESS a Cancer? 15:18 Peptides That May LOWER Cancer Risk (GLP-1's, TA1, & More) 20:18 The Data Problem With Every Peptide (& Why They're All Different) 21:32 Melanotan I & II 28:59 GH Peptides (CJC-1295, Tesamorelin, Sermorelin, Ipamorelin) 32:39 IGF-1 LR3 & PEG-MGF 34:37 Follistatin 37:38 BPC-157 41:22 TB-4 & TB-500 46:01 Arsenic & Other Contaminants in the Vial 48:20 If Peptides Caused Cancer, Wouldn't We Know By Now? 52:11 Everyday Cancer Risks for Comparison 55:38 Estimated Risk - GH Peptides, IGF-1 LR3, & PEG-MGF 58:38 Estimated Risk - Follistatin & Melanotan I & II 01:01:14 Estimated Risk - BPC-157 01:04:53 Estimated Risk - TB-4 & TB-500 01:07:18 What To Do With This Information - Risk-Benefit Analysis 01:10:33 How To Lower Your Cancer Risk From Peptides Get the free peptide guide at my website: quinnstillsonmd.com Subscribe for weekly videos on peptides, longevity & performance! Medical Disclaimer This video is for educational purposes only and does not constitute medical advice. Most peptides discussed are not FDA-approved and are available for research purposes only. Long-term safety and cancer risk in humans have not been established—all risk estimates in this video are informed approximations based on mechanisms and comparator data, not direct human evidence. Always consult a qualified healthcare provider before starting any peptide or medical therapy. #Peptides #BPC157 #TB500 #CancerRisk #CJC1295 #Melanotan #Longevity
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    1 ora e 15 min
  • Retatrutide Masterclass: How To Use It Optimally (Dose, Frequency, Diet, Exercise, & Supplements)
    Jun 26 2026
    Retatrutide is the most powerful weight loss peptide ever studied—but the drug is only half the equation. HOW you use it determines whether you walk away lean, strong, and metabolically healthier, or whether you lose muscle, watch your skin and hair suffer, tank your energy, and STILL leave fat loss on the table. The same appetite suppression that makes Retatrutide so effective is exactly what gets people into trouble when they lose weight too fast. In this video, Dr. Quinn Stillson (MD + strength coach) breaks down the complete practical framework for using Retatrutide optimally—the monitoring, training, diet, supplementation, and the full dosing, frequency, timing, and cycling strategy. Every recommendation is built from the clinical evidence and tied back to the single most important variable: finding YOUR optimal rate of weight loss. This is Part 2—the "how to" guide. If you haven't decided whether Retatrutide is right for you yet, watch Part 1 first. In this video, you'll learn: Why your speed of weight loss is the master variable—and how it drives muscle, bone, skin, hair, and metabolic outcomes The complete lab panel to run on Reta, how often, and how to interpret it Vitals monitoring: resting heart rate, HRV, and blood pressure—and when they signal it's time to stop How much lean mass loss is too much (and why "lean mass" isn't what you think) The optimal exercise routine: resistance training specifics + fasted zone 2 cardio logic Tier 1–3 diet framework: calorie deficit, protein targets, hydration, timing, and quality How to avoid GI side effects (nausea, constipation, and the nausea spiral) The top supplements on Reta—plus collagen, calcium, and EAAs Why oral/sublingual Reta is a scam and it must be subq The four dosing principles and your best STARTING dose for YOUR situation Dose escalation: how and when to move up (and why the standard max dose is too high) Should you split your dose across the week? What the data actually shows Best time of day to inject—optimizing for tolerability over efficacy How long to stay on, whether to cycle, weaning, and switching to other GLP-1s Best for: – Anyone currently on or starting Retatrutide who wants to use it optimally – People worried about losing muscle, hair, or skin quality on a GLP-1 – Lifters and athletes wanting to protect lean mass during weight loss – Biohackers and clinicians wanting an evidence-based protocol, not a one-size-fits-all cycle – Anyone who watched Part 1 and is ready for the practical guide Timestamps 00:00 Why Using Retatrutide Incorrectly is Ineffective and Dangerous 01:50 Optimal Rate of Weight Loss - The Dangers of Losing Weight Too Fast 06:55 Lab Monitoring - Lab Panel, Frequency, and How to Interpret 12:59 Vitals Monitoring - Heart Rate, HRV, Blood Pressure 15:32 Body Composition Monitoring - How Much Lean Mass Loss is Too Much? 23:25 Optimal Exercise Routine - Specifics for Strength Training and Cardio on Reta 28:30 Diet - Best Calorie Deficit, Amount of Protein, and Water 34:20 Diet - Protein Timing + Quality & Carbs with Reta 39:24 How to Avoid Side Effects (Nausea, Constipation, etc) 41:07 Best Supplements on Reta - Top 5 + Collagen, Calcium, EAA’s 46:12 Form of Administration - Can You Take Retatrutide Orally? 46:58 Dosing Principles - Variable Responses and Balancing Efficacy, Cost, & Side Effects 48:38 Best Starting Dose Depending on YOUR Situation 53:31 Dose Escalation - How and When to Increase Your Dose 59:38 Max Dose for Retatrutide - Why the Standard Max Dose is Too High 01:00:57 Optimal Frequency - Should You Split Up Your Reta Dose Throughout the Week? 01:05:24 Best Time of Day to Inject Reta - Optimizing for Side Effects and Efficacy 01:07:19 How Long to Stay on Reta - Should You Cycle? When to Switch to Other GLP-1s? Get the free peptide guide at my website: quinnstillsonmd.com Purchase the Hume Body Pod below (FSA/HSA eligible) — up to 50% off! Code: QUINN https://humehealth.com//discount/QUINN?redirect=/pages/hume-body-pod&utm_source=youtube&utm_medium=influencer&utm_campaign=QUINN Watch Part 1 First Is Retatrutide ACTUALLY Right for YOU? → https://youtu.be/n-XZulcXpZs Subscribe for weekly videos on peptides, longevity & performance! Medical Disclaimer This video is for educational purposes only and does not constitute medical advice. Retatrutide is not FDA-approved and is currently available for research purposes only. Long-term safety and efficacy in humans have not been established. Always consult a qualified healthcare provider before starting any peptide or medical therapy. #Retatrutide #GLP1 #Peptides #WeightLoss #Tirzepatide #Semaglutide #Longevity
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    1 ora e 15 min
  • Full Body MRI: Who Should (& Should Not) Get One
    Oct 17 2026
    Should you get a full body MRI? Most people decide based on cost. That's the wrong question. Even with unlimited money, for the average person the scan sends roughly 10 people down a path of potential harm for every 1 it potentially helps. But there is a specific group of people where it's worth it, and this video shows you how to find out if you're one of them. In this video, Dr. Quinn Stillson (MD, A4M board-certified in longevity medicine) walks through the actual evidence on whole body MRI screening, the kind sold direct-to-consumer by Prenuvo, Ezra (now Function Health) and others: what a standard scan can and can't see, how likely it is to find something that matters for YOU, the real numbers on incidental findings, biopsies and overdiagnosis, and a step-by-step framework for deciding. No sales pitch, no "it's a scam." Just the data, finding by finding. The result: a three-tier system for who should get one, who shouldn't, and how to do it right if you do. In this video, you'll learn: Why a full body MRI is NOT the same as an MRI of every body part (and what that costs you in detail) The cancers it actually sees well vs. the ones it's nearly blind to (colon, breast, lung, prostate) Which sequences a scan needs (T1, T2, STIR, DWI, Dixon) and the tell for a scan that's skipping them The add-ons: brain MRA, FLAIR, volumetrics, cardiac strain, body composition. Which are worth it The real cancer detection rate (1.57%) and how your genes, family history and medical history change it The non-cancer findings that can change what you do: fatty liver, AAA, spine fractures, pancreatic cysts, brain aneurysms, meningiomas Tracking data (brain volume, muscle quality, organ volumes): what the scan adds over DEXA and bloodwork Why ~30% of people get an indeterminate finding and only 2-4% have something serious The hidden costs: anxiety, extra imaging, radiation, biopsies, surgery for benign findings Overdiagnosis: why 42-58% of screen-detected kidney cancers were never going to hurt anyone The decision framework: elevated AND spread-out risk, the tracking gate, age, and anxiety The three tiers (and the "do not get one" list) How to do it right: the 3 questions to ask the provider, ONCO-RADS, and planning repeat scans Best for: – Anyone considering a Prenuvo, Ezra or other direct-to-consumer full body MRI – People with a family history or genetic risk trying to figure out if the scan actually helps them – Longevity enthusiasts who want the tracking data and need to know if it's worth it – Anyone who already got one and is staring at an "indeterminate finding" – Clinicians who want the numbers, not the marketing Timestamps 00:00 Should You Get a Full Body MRI? Why This Is Not a Cost Question 01:51 Full Body vs Dedicated MRI - Why It Sees Less 03:54 Cancers It Detects & Misses 05:38 Other Findings It Detects & Misses (Aneurysms, Cysts, Fractures, Etc) 07:10 Not All Scans Are Equal: Sequences & Skimping 09:11 Add-Ons - Body Comp, Brain MRA & Volumetrics, Heart Strain, Organ Aging 11:12 Cancer Detection Rate in YOU & Why It's Individualized 12:50 Genes, Family History, & Medical History: What Raises YOUR Odds 15:42 Fatty Liver, AAA & Spine Fractures 18:19 Pancreatic Cysts, Heart Strain & Brain Aneurysms 21:30 Tracking: Muscle Quality, Brain Volume, & Organ Aging 23:28 Risk #1 - The 30% Problem (Indeterminate Findings) 24:54 Anxiety, Extra Imaging, Biopsies & Surgery 28:31 Overdiagnosis - Was the Cancer ACTUALLY Going to Hurt You? 31:26 Should YOU Get One? The 2 Conditions (Elevated AND Spread Out Risks) 35:05 Tracking Data: Worth It? 36:34 Age & Anxiety: The Final 2 Decision Makers 38:02 The 3 Tiers of Use Cases (& Who Should NOT Get One) 40:30 Do It Right, Steps 1-3 - What to Ask, Which Add-Ons, & Results Plan 42:45 Do It Right, Steps 4-5 - Screenings & Repeat Scans Get the FREE Full Body MRI Decision Guide (every risk factor, every number, and the walkthrough from this video): https://www.quinnstillsonmd.com/home#mri-guide Subscribe for weekly videos on peptides, longevity & performance! Medical Disclaimer This video is for educational purposes only and does not constitute medical advice. Imaging and screening decisions should be made with a qualified healthcare provider who knows your personal and family history. Nothing here is a recommendation for or against any specific scan, provider, or treatment. #FullBodyMRI #WholeBodyMRI #MRIScreening #Longevity #CancerScreening #PreventiveMedicine #Biohacking
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    46 min
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