Welcome back to Cardiovascular Therapeutics Unplugged! In today's episode, we dive into the rapidly evolving world of structural heart disease, where cutting-edge catheter-based valve therapies are reshaping how we treat faulty heart valves. For decades, open-heart surgery was the only path for patients with failing valves—often leaving older or high-risk individuals without options beyond, "You're not a candidate." But that's no longer the case.

Join Dr. Mehra he breaks down the basics of heart valve function, what happens when valves fail, and how innovations like TAVR (Transcatheter Aortic Valve Replacement) are expanding treatment to more patients than ever before. We'll cover who qualifies for these revolutionary procedures, how outcomes compare to traditional surgery, the role of the heart team in patient care, and the critical questions every patient should ask to be sure they're exploring all their options.

Whether you're a clinician, patient, or just curious about advances in cardiology, this episode will give you a clearer understanding of the therapies changing the lives of people with valvular heart disease.

00:00 Understanding heart valves and function

04:15 Heart valve dysfunction issues

08:53 Understanding Severe Aortic Stenosis

11:28 Introducing the new heart valve technique

13:41 The necessity of alternative treatments

17:01 Discussing surgical options for valve issues

20:50 Mitral valve regurgitation treatment options

24:18 Awareness and evolution of therapies

28:54 Structural heart team approach

31:36 Encouraging patient self-advocacy

34:53 Options for catheter valve therapy

Welcome to another episode of Cardiovascular Therapeutics Unplugged. Today Dr. Mehra pulls back the curtain on one of cardiology’s most common and most misunderstood procedures: the coronary stent. When a stress test comes back abnormal, “stent” is often the word that follows, and for many patients, it sounds urgent and final. But is it always the right move? In this episode, we confront the myths and explore the evidence, showing when a stent can save a life, when medication is just as effective, and how to cut through fear to ask the questions that matter most. If you or someone you love has ever been told you need a stent, this is the episode you cannot afford to miss.

00:00 How stents work in arteries

06:50 Stent decision criteria and FFR

09:12 Understanding heart attacks and treatments

12:21 Discussing the Courage trial results

16:20 Heart attack interventions and treatments

19:26 Using medical therapy for heart disease

23:51 Discussing procedure risks with patients

27:12 Discussing second opinions with patients

29:44 Talking with cardiologist about options

32:46 The benefits of patient involvement

Most patients diagnosed with atrial fibrillation (AFIB) are handed a prescription for blood thinners often without ever learning about another potentially life-changing option. In this episode of Cardiovascular Therapeutics Unplugged, Dr. Aditya Mehra deep dives into the two main tools for stroke prevention in AFIB: traditional anticoagulants and the innovative Watchman device. He breaks down how blood clots form in the heart, why stroke prevention must be one of the very first conversations in AFIB care, and what patients need to know to make the right decisions for themselves. Whether you’re newly diagnosed, struggling with the side effects of blood thinners, or simply curious about new advances in heart treatment, this episode arms you with the questions and answers that could shape your journey.

00:00 Discussing atrial fibrillation tools

06:44 Understanding Atrial Fibrillation Basics

10:08 Left atrial appendage and heart function

13:33 Assessing bleeding risk with HAS-BLED score

17:08 Addressing anticoagulation gaps

18:22 Stroke risk in elderly patients

23:17 Watchman device heart procedure

26:55 Comparing Watchman device to warfarin

31:36 Patient awareness of new tech

33:02 Discussing patient education on AFib

36:19 Discussion on AFIB stroke prevention