• Episode 615: Vape Expectations: Are electronic cigarettes the real deal for smoking cessation?
    Jan 19 2026
    In episode 615, Mike and James revisit the evidence around using electronic cigarettes for smoking cessation. We look at smoking cessation rates between the use of e-cigarettes, nicotine-free e-cigarettes, nicotine replacement therapy or varenicline. Tune in to hear about the numbers from the trials – it may inform you as to what you could recommend […]
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    24 min
  • Episode 614: Nipple Confusion or Nonsense? Pacifiers and Breastfeeding Duration
    Dec 28 2025
    In episode 614, Mike and James discuss with Caitlin Finley the evidence around a very common primary care question. Does restricting early use of pacifiers result in higher rates of breastfeeding up to 6 months of age in term infants? We discuss the findings and do our best to put the evidence into context. Show […]
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    24 min
  • Episode 613: Doxycycline for post-exposure prophylaxis of sexually transmitted infections
    Dec 11 2025
    In episode 613, Mike and James discuss with Jessica Kirkwood the evidence for post-exposure prophylaxis of sexually transmitted infections. We go over the 4 RCTs that have looked at the value of a single dose of doxycycline. It does reduce the risk for some specific infections – but as always you need to know the […]
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    21 min
  • Episode 612: Can fezolinetant improve vasomotor symptoms in menopause?
    Nov 23 2025
    In episode 612, Tina and James chat with Samantha Moe about the use of a recently approved non-hormonal medication being used for vasomotor symptoms in menopause. We go over the 3 available trials and show you the numbers, talk about the limitations and then put the results into the context of hormone and other non-hormonal […]
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    24 min
  • Episode 611: Meds for Essential Tremor: Steady solution or shaky science?
    Nov 7 2025
    In episode 611, Tina and James talk with Samantha Moe about the use of betablockers and other medications for essential tremor. There is some evidence – much of it from the 1970s, but also some more recent publications. We do our best to tease out all the numbers you need to help you with your […]
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    25 min