Episodi

  • Skin Barrier Structure & Function
    Nov 22 2025

    In this episode, we break down what the skin barrier actually is, where it sits in the skin, and why it’s essential for hydration and protection. We cover the stratum corneum’s “brick-and-mortar” structure, the roles of corneocytes, lipids, and filaggrin, and how the acid mantle and microbiome support barrier health from above. We also clarify the difference between sebum on the surface and the lipid matrix within the barrier.

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    11 min