Watch the FULL podcast here: https://youtu.be/qHFymGgsYyECan you do everything right and still face Alzheimer’s risk? It can happen, and we discuss how environmental toxins, metabolic health, and shifting hormones may play a role. This clip explores two grandmothers with opposite lifestyles, highlighting possible factors like hemoglobin A1c, menopause-related drops in estrogen, and other hormones including IGF-1 and thyroid. We also consider genetic resilience and detox capacity, and why relying on luck isn’t wise. Women are addressed directly, with advice to see a good hormone doctor during perimenopause and menopause. ***This episode is sponsored by:NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/***Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

Watch the FULL podcast here: https://youtu.be/yZDzsfNjG_M

Curious what Akkermansia actually does for your health? It’s discussed here as a keystone gut microbe linked to improved insulin sensitivity, lower A1C in clinical studies, GLP-1 release and healthier blood vessels, with associations to cancer immunotherapy response. This clip explores the gut brain circulation connection, how metabolism and energy relate to this microbe, and why people considering immunotherapy might also focus on gut health. We also touch on the importance of discussing immunotherapy with an oncologist and staying within medical advice boundaries.

***

This episode is sponsored by:

NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/

Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes

👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!

📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah

🐦 Twitter: https://x.com/SarahAnnMacklin

📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

We spend so much of our lives trying to be impressive. We polish our edges and hide our cracks because we’re terrified that being "real" means being weak. But what if the very things we are hiding are actually the only bridges to real connection? It is a scary thought, but one that completely changes how we show up in the world.

Here’s what we explore together:

- Why being "invulnerable" is sometimes just as important as being open and how to know the difference.

- How accepting your own foolishness can actually make you invincible to humiliation.

- Why we feel "boring" with some people and alive with others and why it is not your fault.

- How to use curiosity to metabolize pain and crisis into understanding.

- Why following your "gut" in love can sometimes lead you straight into disaster.

- Why the truth sometimes needs to be delivered in "small pieces" to be heard.

- Why a functioning relationship is the most difficult achievement of a human life.

- How to find a path that fits your unique nature in a world that wants you to conform.

Love, Sarah Ann 💛

***

This episode is sponsored by:

NOWATCH: The compassionate health tracker

Connecting body and mind with unique stress recovery insights so you can live fully today

15% off with code LWBW15 at https://nowatch.com/

Mojo: the app for expert-led courses in better sex.

Learn from world-class sex therapists and relationship experts with courses tailored to your needs.

15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg Out

How to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out

Reset Your Health

If your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.

Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.

https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve

👉 If this resonates, you can join the thousands who read

The Compassionate Cure each week. https://sarahmacklin.substack.com/

***

Let’s be friends!

📷 Instagram: https://www.instagram.com/sarahannmacklin/

📹 Subscribe:http://www.youtube.com/@livewellbewellsarah

🐦 Twitter: https://x.com/SarahAnnMacklin

📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast

💌 Newsletter: https://sarahmacklin.substack.com/

***

If You Enjoyed This Episode, You Might Also Like:

The 7 Pillars to Finding Genuine Love Beyond Dating Apps | Francesca Hogihttps://youtu.be/aGqlB61ldoA

***

Sign up to Sarah’s Compassionate Cure newsletter:

Science Simplified, Health Humanised.

Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact.

https://sarahmacklin.substack.com/

***

Highlights

00:00:00 Intro

00:00:24 The Vulnerability Paradox: When to Put Your Wall Up

00:02:44 Connection as a Risk: Gateways to Friendship

00:03:45 The Power of Declaring Yourself an "Idiot"

00:06:25 Shared Humanity: Kings, Philosophers, and Us

00:10:20 Why We Feel Different with Different People

00:12:12 Curiosity as a Survival Mechanism for Pain

00:13:58 Relationships: The Hardest Thing We Do

00:16:02 The Dangers of "Instinct" in Love

00:26:57 The Cruelty of Ghosting and Lack of Closure

00:29:41 Understanding Self-Compassion Through Heartbreak

00:47:43 Philosophy vs Psychotherapy: How We Absorb Truth

01:08:00 Managing Moods: Why Happiness comes in 15-Minute Bursts

01:13:09 Defining Success: Fitting Your Nature to the World

01:31:20 Why We Sometimes Refuse the Love We Want

***

Love what you’re hearing?

My small ask is to please rate and review Live Well Be Well. This helps the show expand and allows me to keep producing these with the best quality guests. It means a huge amount to me, so thank you.

Watch the FULL podcast here: https://youtu.be/HHvG8HEYdjA

Are we built to manage only about 150 meaningful relationships, and what does that mean for our health? It matters because small, real-world connections help lower loneliness-driven stress that can worsen heart disease prognosis and raise some cancer risk. This clip explores the 150-person social limit, why in-person cues beat screens, a call-based study that eased loneliness, concerns about AI companions and hyper-independence, and lessons from hunter-gatherers on movement, sleep, and mood. Together we consider balancing fast tech with our unchanged human needs.

***

This episode is sponsored by:

NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/

Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes

👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!

📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah

🐦 Twitter: https://x.com/SarahAnnMacklin

📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

Can specific gut and mouth bacteria influence brain health and conditions like Parkinson's or Alzheimer's? We look at early clinical work on Lactobacillus plantarum PS128 and its potential to slow Parkinson's progression, links between gum disease and dementia, and how Lactobacillus reuteri may stimulate oxytocin. This clip explores the gut-brain and oral-brain connections, the idea of a brain microbiome, and emerging views on brain regeneration and healthy aging.

***

This episode is sponsored by:

NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/

Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes

👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!

📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah

🐦 Twitter: https://x.com/SarahAnnMacklin

📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

Ever feel like you’re waking up as two different people depending on the week of the month? One week you’re taking on the world with total confidence, and the next, you’re second-guessing every decision you’ve ever made. It turns out, that isn’t just "you being emotional", it’s actually a sign of your brain responding to a very specific biological rhythm.

This week on Live Well Be Well, I’m sitting down with the brilliant Dr. Sarah Hill. She’s an evolutionary psychologist and the author of This Is Your Brain on Birth Control and The Period Brain. Sarah has this incredible way of explaining how our hormones like estrogen, progesterone, and testosterone, aren’t just about reproduction; they are actually "wise advisors" that shape how we think, who we’re attracted to, and how we show up in our work and relationships.

Here’s what we explore together:

- Your Hormones as Information: How these biological signals act as internal guides for your behavior and motivation.

- The "Two Advisors" Theory: Why feeling different across your cycle actually makes you a better, more well-rounded decision-maker.

- The Power of Progesterone: Why this often-ignored hormone is actually a neuroprotective "superpower" that helps your brain slow down and recover.

- Cycle Variability: Why your "symptoms" can change every month based on everything from sleep to stress.

- The Male Perspective: A fascinating look at how men’s testosterone is actually more reactive to the environment (like sports or competition) compared to the predictable cycles of women.

- Bridging the Cultural Gap: How to stop overriding your body’s natural cues in a world that expects you to be the same person every single day.

Love,

Sarah Ann 💛

***

This episode is sponsored by:

NOWATCH: The compassionate health tracker

Connecting body and mind with unique stress recovery insights so you can live fully today

15% off with code LWBW15 at https://nowatch.com/ Mojo: the app for expert-led courses in better sex.

Learn from world-class sex therapists and relationship experts with courses tailored to your needs.

15% off with code LiveWell15 at mymojo.com/livewellbewell

***

The Great British Veg Out

How to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out

Reset Your Health

If your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.

Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.

https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve

👉 If this resonates, you can join the thousands who read

The Compassionate Cure each week. https://sarahmacklin.substack.com/

***

If You Enjoyed This Episode, You Might Also Like:

Women's Brain Health: What Science REALLY Says About Hormones, PMS & Menopause | Dr Sarah McKay

https://youtu.be/aKnS1McNVm8?list=PLfXKbjBGaUhb7iE0BaE2PZINeLZ3Ybb0M

***

Highlights

Intro (00:00:00)

The Wisdom of the Menstrual Cycle (00:01:55)

The Luteal Phase: The Dark Side of the Cycle (00:04:42)

Men's Hormones vs. Women's Hormones (00:11:46)

The Impact of Hormones on Behavior (00:17:37)

Tracking Your Cycle for Better Understanding (00:23:25)

PMS: Understanding and Reframing (00:29:49)

Evolutionary Perspectives on Attraction (00:36:38)

Research on Birth Control and Relationship Satisfaction (00:41:29)

Scent and Attraction (01:01:00)

Sexual Orientation and Hormonal Influence (01:07:51)

Menopause and Attraction (01:11:02)

Communication and Understanding in Relationships (01:19:03)

The Importance of Recognizing Biological Differences (01:28:35)

Can boredom and daydreaming actually boost creativity and calm? Here, I’m discussing how a solo writing sprint in nature left my HRV higher and my mind clearer, then we examine the default mode and executive networks, task switching, and screen-free habits. This clip explores the Meals, Bedroom, Bathroom rule for no phones, the value of nature time, and reframing boredom as daydreaming to restore the brain. We talk practical steps for dopamine-heavy habits, why reflection improves decisions, and how daydreaming can spark ideas and support mental health.

Watch the FULL podcast here: https://youtu.be/ZoyEJ0WD99g

***

This episode is sponsored by: NOWATCH: Health tracking reimagined

Know your body, trust yourself.15% off with code LWBW15 at nowatch.com

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes

👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

Watch the FULL podcast here: https://youtu.be/qHFymGgsYyE

Worried about Alzheimer’s and what you can do now? You’ll hear practical, testable steps to lower risk by targeting metabolism, inflammation and toxins, plus daily habits for brain rest and sleep. This clip explores the idea that Alzheimer’s can have different drivers, the importance of early testing (continuous glucose monitors, hs-CRP, urine toxin tests), and simple changes like meditation, less phone time, better sleep, air purifiers, filtered water, non-toxic skin products, and eating organic while avoiding ultra-processed foods.

***

This episode is sponsored by:

NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com

***

The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes

👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

***

Let’s be friends!

📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah

🐦 Twitter: https://x.com/SarahAnnMacklin

📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/