Can we actually reverse aging — and could that cure Alzheimer's?

Physician and aging researcher Dr. Michael Fossel — Stanford MD/PhD, decades studying cellular aging and telomeres, author of Reversal: Science, Medicine, and a Future Beyond Aging — joins Steph Pliha on Leadr. Podcast to answer one of medicine's biggest questions: why we age and if we can reset it.

This isn't just science. We get into why aging is a failure of maintenance (not just entropy), why age is the #1 risk factor for Alzheimer's, where cell aging fits between upstream risks and downstream biomarkers, and why his lab first reversed aging in human cells in 1998. Plus: what actually protects brain health — nutrition, inflammation, insulin resistance, sleep, exercise — vs what is hype, and what his team at Telocyte is building now to make treatment accessible.

You'll learn:

• Why aging isn't "wear and tear" — and what actually drives it

• The cellular link between aging and Alzheimer's

• What you can do today for brain health (that your grandma already told you)

• When human trials to reverse aging could happen — and what "cure" really means

• Consciousness, compassion, and his year babysitting Koko the gorilla at Stanford

Guest: Dr. Michael Fossel - Book: Reversal | Telocyte: telocyte.com

Host: Steph Pliha, Founder & CEO of Tribe Consulting — Make Your Brand a Verb™ — stephpliha.com | tribeconsulting.co

Find Dr. Michael Fossel:

Book — Reversal: Science, Medicine, and a Future Beyond Aging: www.amazon.com/dp/B0GKNGSL2X

Telocyte: www.telocyte.com

Find Steph & Leadr. Podcast:

Tribe Consulting: https://www.tribeconsulting.co/

Steph Pliha: https://stephpliha.com/

Leadr. Podcast: https://stephpliha.com/leadr-podcast

Instagram: @stephpliha | LinkedIn:/in/stephpliha

Watch on YouTube: https://youtu.be/jAV23FTZxRQ

In this episode of Leadr. Podcast, Steph Pliha sits down with Dr. Alexander Grinberg, physician, longevity specialist, and founder of Infinity Epigenetics, for a fascinating conversation about the future of human health, aging, and regenerative medicine.

With more than three decades of experience in longevity medicine, Dr. Grinberg explains why living longer isn't simply about adding years to life, it's about improving healthspan, resilience, and performance through a personalized approach rooted in science.

Together, they explore the rapidly evolving world of peptides, GLP-1 therapies, mitochondrial health, fasting, biohacking, genetics, and precision medicine while discussing both the opportunities and limitations of today's longevity movement. Dr. Grinberg also shares why sound judgment, careful experimentation, and understanding your own biology are more important than chasing the latest health trend.

The conversation covers practical strategies for building a stronger foundation for long-term health, the role of inflammation and lifestyle, emerging regenerative therapies, and how artificial intelligence could soon transform personalized medicine.

Whether you're curious about extending your healthspan, interested in biohacking, or simply looking to better understand the science behind healthy aging, this episode offers an evidence-informed perspective on one of medicine's most exciting frontiers.

If you enjoyed this episode, make sure to LIKE and SUBSCRIBE for more conversations exploring leadership, health, neuroscience, artificial intelligence, longevity, and the future of human performance.

Featured Links

Infinity Epigenetics: https://infinityepigenetics.com/

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Tribe Consulting Agency: https://www.tribeconsulting.co/

Steph Pliha: https://stephpliha.com/

LinkedIn: https://www.linkedin.com/company/tribebrand/

Leadr. Podcast Website: https://www.stephpliha.com/leadr-podcast
AIR Protocol (Age in Reverse): https://airlongevity-ldl9uibg.manus.space/

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BUSINESS INQUIRIES:

hello@tribeagency.org

FTC Disclosure: Some links shared may be affiliate links, meaning I may earn a small commission at no additional cost to you.

© 2026 Tribe Consulting Agency, Inc. All Rights Reserved.

In this episode of Leadr. Podcast, Elvin Aghammadzada , AI Architect at Nvidia/DataRobot working with Fortune 50 enterprises, joins the conversation to explore one of the biggest shifts happening in business and the workforce today: the rapid evolution of artificial intelligence and agentic AI.

With a background in computer science and engineering and experience working closely with Fortune 50 companies on their enterprise AI journeys, Elvin offers a firsthand look at how businesses are actually using AI beyond the hype. From AI-powered coding and text generation to autonomous agents capable of taking action, this conversation explores where enterprise AI is today and where it's heading next.

Whether you're a business owner, entrepreneur, employee, student, or simply trying to understand where AI is taking the world, this episode offers a fascinating look at what may be coming next and why learning to adapt may be one of the most important skills of the future.

Find Elvin Aghammadzada: Elvin Aghammadzada | LinkedIn

• ◼ The rapid evolution of AI and its impact on the future workforce
  ◼ AI agents and the rise of the agentic workforce
  ◼ Moving from AI-generated content to AI taking real-world action
  ◼ The AI productivity paradox: doing 10x more but feeling less productive
  ◼ Outcome-based agents, autonomous workflows, and "guardian" agents
  ◼ How Fortune 50 enterprises are applying AI today
  ◼ AI coding, data analysis, and the future of knowledge work
  ◼ AI adoption, enterprise data, security, guardrails, and change management
  ◼ Will AI replace jobs? The future of careers and the workforce
  ◼ The potential for AI to create a shorter workweek and reshape how we live and work
  

If you enjoyed this episode, make sure to LIKE and SUBSCRIBE for more conversations exploring leadership, business, health, neuroscience, artificial intelligence, longevity, and the future of human performance.

FIND US:

Tribe Consulting Agency: Tribe Consulting Agency

Steph Pliha: Home

Leadr. Podcast: Leadr. Podcast | MedTech & Leadership Insights

CONNECT WITH US ON SOCIAL:

📱 Instagram:

@stephpliha - Instagram

📱 LinkedIn:

Tribe Consulting Agency: Tribe Consulting Agency

Steph Pliha: Steph Pliha | LinkedIn

DON'T FORGET TO SUBSCRIBE TO LEADR. PODCAST

ABOUT ME:

I'm Steph Pliha, Founder and CEO of Tribe Consulting Agency with over 20 years of leadership experience. After building multiple seven-figure businesses, I now help entrepreneurs transform their brands from nouns into verbs. My Make Your Brand a Verb™ Framework has helped businesses create stronger positioning, clearer messaging, and lasting market impact.

BUSINESS INQUIRIES:

hello@tribeagency.org

FTC Disclosure: Some links shared may be affiliate links, meaning I may earn a small commission at no additional cost to you.

© 2026 Tribe Consulting Agency, Inc. All Rights Reserved.