In this episode of Rheuminations, guest host Leonard H. Calabrese, DO, sits down with David Chernoff, MD, chief medical officer of SetPoint Medical, to discuss the vagus nerve and recent developments in immune mediated disease.

· The story of Kevin Tracey, MD. 5:08

· Going from cytokines to the vagus nerve to immune mediated inflammatory disease. 7:23

· The ups and downs of non-surgically implanted devices. 13:28

· The pivotal studies. 15:35

· Gadolinium MRI. 24:03

· The gut-brain immune axis. 29:35

We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. Leonard H. Calabrese, DO, can be reached at CALABRL@ccf.org. Follow him @LCalabreseDO.

In this episode of Rheuminations, host Adam J. Brown, MD, will walk you through the history of pleural effusions in rheumatoid arthritis. He discusses topics ranging from fascinating case studies to how pleural effusions are treated today.

· Diving into pleural effusions. 2:38

· What's in the fluid? 12:01

· When did pleural effusions become linked to RA? 15:18

· The glucose talk. 27:04

· Green effusions. 32:40

We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum.

Not all jaw claudication is giant cell arteritis. Hear some interesting cases and learn about things to look for in the labs to suspect an alternative diagnosis along with co-host Leonard H. Calabrese, DO.

· When GCA isn't GCA, walking through mimic cases 2:43

· Infectious mimics 14:36

· Large vessel involvement cases 16:47

· GCA as a medical emergency 22:05

· Erdheim-Chester disease 23:40

We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum.