Overdoses are declining in the United States.

That is worth celebrating.

But what most families do not realize is this: the drug supply is changing fast. And in many ways, it is becoming more unpredictable and more dangerous.

In this episode of Do What You Can Live With, Brandi Mac breaks down what is happening behind the headlines:

• Why fentanyl purity is dropping and what that actually means
• The rise of medetomidine and why Narcan does not reverse it
• Nitazines, synthetic opioids that are far more potent than fentanyl
• The methamphetamine surge and what makes today's supply different
• Why prohibition history matters
• What "safe supply" really means and why it is being debated
• Why rock bottom in 2026 can mean death
• How families can stay connected without shame

Drawing from her experience as a critical care nurse practitioner and as a mother of a daughter in recovery, Brandi explains why old advice like "they have to hit bottom" is increasingly dangerous in today's unregulated drug market.

This is not about politics.

This is about survival.

If you love someone in active addiction, this episode will help you understand:

1. Why the drug your loved one used last week may not be the same this week

2. Why Narcan still matters, even with tranquilizers in the supply

3. Why connection is not enabling

4. Why you have to decide what you can live with

Addiction is not disappearing.

The supply will keep shifting.

The question is how you will show up.

If this episode resonates, please follow, leave a review, and share it with someone who needs it. Families deserve information without shame.

Follow Brandi on social media: the_original_brandi_mac

Email: brandi@brandimac.com

Website: http://www.brandimac.com

Purchase Brandi's book "Do What You Can Live With: A Survival Guide for Families Navigating Addiction, Grief and Impossible Choices" on Amazon

Alcohol is the most normalized drug in America and one of the deadliest.

In this episode of the Do What You Can Live With Podcast, critical care nurse practitioner and author Brandi Mac exposes how the trillion-dollar alcohol industry shaped the language we use around addiction, influenced federal policy, and helped keep alcohol socially acceptable while millions of families quietly suffer.

Alcohol kills an average of 178,000 Americans every year, more than all drug overdoses combined. Yet it remains legal, advertised, and culturally protected. That did not happen by accident.

In this episode, Brandi breaks down how corporate lobbying influenced federal agencies like the Center for Substance Abuse Prevention, why alcohol was intentionally separated from the word "drug," and how terms like substance abuse were shaped by profit, not families, clinicians, or people in recovery.

Backed by peer-reviewed research and decades of frontline ICU experience, this episode connects the dots between policy, stigma, and the invisible grief of loving someone with alcohol use disorder.

• Why alcohol is classified as a Group 1 carcinogen by the World Health Organization

• How alcohol kills more people than fentanyl, heroin, meth, and cocaine combined

• The role of corporate lobbying in changing federal addiction language

• Why alcohol harm receives a fraction of the funding compared to other diseases

• How the separation of "alcohol and drugs" shaped stigma and shame

• Why families affected by alcoholism are often dismissed and minimized

• What boundaries, love, and clarity look like when the system fails you

Brandi also explores how lobbying dollars dwarfed public health funding, how Big alcohol companies profit off the sickest drinkers, and why harm reduction has worked for drug overdoses but remains taboo when applied to alcohol.

This episode is for parents, partners, siblings, clinicians, and anyone who has been told "it's just alcohol" while watching someone they love disappear.

Because your pain was not imagined.
Your crisis was not invisible by accident.
And you are not wrong for taking it seriously.

📘 Learn more at brandimac.com
📖 Author of Do What You Can Live With

What does "rock bottom" really mean when you love a child in active addiction?

In this episode of the Do What You Can Live With podcast, I sit down with Melissa Ledesma, a mother who lost her daughter, Angel, to a cocaine overdose in 2023. Not fentanyl. Not opioids. Cocaine.

Melissa shares the truth about grief that lingers years later, the shock of reading an autopsy report that did not match public assumptions, and what it actually looks like to love a child through addiction without abandoning them to shame or isolation.

We talk about stimulant overdoses, harm reduction, sibling dynamics, trauma, and the painful myth that families must step away to force change. This is an honest conversation for parents, caregivers, and anyone carrying grief that does not move on a timeline.

Content note: This episode discusses overdose, child loss, and grief.

In this episode:

• What "rock bottom" really looks like for families

• Cocaine and stimulant overdoses without opioids

• Why Narcan does not reverse stimulant overdoses

• Harm reduction, MAT, and what Melissa wishes she knew sooner

• Loving your child without losing yourself

Resources & Links:

• Melissa on TikTok: @the.real.melissa

• Melissa on Facebook: Melissa Ledesma

• Do What You Can Live With by Brandi Mac (Amazon)

• Family resources and support: brandimac.com

If this episode resonated, consider subscribing and leaving a review. It helps other families find conversations like this when they need them most.