John Clellon Holmes met Jack Kerouac on a hot New York City weekend in 1948, and until the end of Kerouac's life they were—in Holmes's words—"Brother Souls." Late one night as they sat talking, Kerouac spontaneously created the term "Beat Generation" to describe this new attitude they felt stirring around them. Brother-Souls: John Clellon Holmes, Jack Kerouac, and the Beat Generation is the remarkable chronicle of this cornerstone friendship and the life of John Clellon Holmes.

From 1948 to 1951, when Kerouac's wanderings took him back to New York, he and Holmes met almost daily. In a burst of creation in April 1951, he drew all the materials he had been gathering into the scroll manuscript of On the Road.

Biographer Ann Charters was close to John Clellon Holmes for more than a decade. At his death in 1988 she was one of a handful of scholars allowed access to the voluminous archive of letters, journals, and manuscripts Holmes had been keeping for twenty-five years. In that mass of material waited an untold story. Through the pages of Holmes's journals, often written the morning after the events they recount, Charters discovered and mined an unparalleled trove describing the seminal figures of the Beat Generation: Holmes, Kerouac, Neal Cassady, Allen Ginsberg, William Burroughs, Gregory Corso, and their friends and lovers.