In commemoration of the 60th anniversary of President John F. Kennedy's assassination, Who Killed JFK? explores the pressing questions that still surround one of the most tragic moments of the 20th century. Award-winning journalist Soledad O'Brien and beloved filmmaker Rob Reiner team up to discover the truth behind the assassination, revealing how the ramifications of the 1963 tragedy still impact American society today.

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Who wanted the president dead? And is the unexpected murder of the lead suspect the first clue in the answer to this mystery? Our hosts, Rob Reiner and Soledad O’Brien, discuss why the question “Who Killed JFK?” endures in the American imagination 60 years later. Did President Kennedy have a target on his back when he transformed from ‘Cold Warrior’ to global peacemaker?

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Was there a coverup? The Warren Commission published a report in 1964 that claimed Lee Harvey Oswald was the sole gunman. But over a decade later, the House Select Committee on Assassinations claimed that President Kennedy was killed as the result of a ‘conspiracy.’ Why the conflicting results? With revelations over the last 60 years, flaws in both investigations are exposed.

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What does the forensic evidence reveal? We start at the scene of the crime, move to the hospital and end with the strange autopsy. And with breaking news from one of Kennedy’s Secret Service Agents, the Single Bullet Theory will finally be put to rest.

A big thank you to The 6th Floor Museum at Dealey Plaza and WFAA TV Collection.

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Who was Lee Harvey Oswald? We dig deep into Oswald’s story. Starting with his childhood, talking directly to people who knew him, we explore his time in the military and his curious defection to the Soviet Union at the height of the Cold War. Was he just a disgruntled ex-Marine, a lone wolf who wanted to take down a president? Or was he part of something bigger?

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What did Oswald mean when he uttered the now-famous words “I’m just a Patsy!”, just hours before he was murdered? To begin to understand what those words mean, we step into the ‘Wilderness of Mirrors’ to see the world of counterintelligence through the eyes of James Jesus Angleton – a man known as “The Poet Spy.” In the Wilderness, confusion is a key weapon. We’ll trace Oswald’s steps from his return from the Soviet Union to his activities in New Orleans in the summer of 1963.

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Who is Richard Case Nagell, and why did he mysteriously rob a bank two months before President Kennedy was assassinated? We’ll continue to follow Oswald’s movements, including how he got a job in a building that overlooked the President’s motorcade route. We’ll discuss a CIA plan that might be the smoking gun. The plan that exposes the conspiracy: Operation Northwoods.

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Who had the motive? We explore the three groups who had both motive and means to assassinate Kennedy: the Mafia, the Cuban Exiles, and the intelligence community. And we uncover the unexpected ways they were working together.

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