The VPZD Show copertina

The VPZD Show

The VPZD Show

Di: Drs. Vinay Prasad & Zubin Damania
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Two doctors, one podcast, Alt-Middle as heck. Featuring Dr. Vinay Prasad (host of Plenary Session) and Dr. Zubin Damania (host of The ZDoggMD Show).All rights reserved Disturbo fisico e malattia Igiene e vita sana Politica e governo Scienza
Episodi
  • Elizabeth Holmes Doc, Pope Leo Cancer, Bryan Johnson Genome

    Elizabeth Holmes Doc, Pope Leo Cancer, Bryan Johnson Genome
    Oct 20 2026
    The all-new Nissan Nystagmus: Deviate your Driving! 😁 It's VPZD Ep. 46, ⁠originally streamed LIVE on YouTube⁠. Chronological topic list Housekeeping: clarifying brain death versus severe brain damage, and why a competent examiner matters Zubin’s first travel speaking engagement in three years, a pain medicine panel in Dallas, and the Rodeo Goat burger Vinay’s panel at a biotech conference and the longevity target question Elizabeth Holmes and Theranos, and how John Ioannidis spotted the lack of peer reviewed papers Why you can’t run 100 tests off a single drop of blood Zubin’s Theranos lipid panel at TEDMED and whether the numbers were real Finger sticks versus venipuncture, and why lancets hurt The Nathan Fielder documentary and the 35 days before federal prison Holmes’s personality, her belief that the machine works, and “Theranos 2.0” Puppeteer or puppet: Billy Evans, Sunny Balwani, and the men in her life Amanda Seyfried’s reenactments and the second half of the film Did she commit fraud, did it harm patients, and was she scapegoated for flying too high Why Holmes picked a claim that could be tested in minutes, and the harder to falsify claims in biotech Health influencers, creatine, and observational studies as placebo Stanford versus Berkeley, and the CAC score as a better measured number than Theranos A glioblastoma device and the ambiguity of its trial Whether Holmes really didn’t understand the “Who’s on First” joke Spiritual people, pop culture, and why VPZD isn’t cognitive dissonance Pope Leo’s lung cancer: luck or Providence, lead time bias, or an indolent tumor Why Pope Leo’s case gets spun as proof that screening works, and the case against scanning non-smokers Whether adenocarcinoma, secondhand smoke, and a Peruvian mission shaped the diagnosis The Pope’s reported equanimity, and the politics of the papal job A New York Times Daily episode on Texas Trump voters, and why a cherry-picked anecdote isn’t a poll Why polling is a flawed science, plus spam calls and the “right to be left alone” Indian call center scammers and YouTube videos of people hacking them AI car dealership calls, and medical car names like the Ford Infarct and the Toyota Tetralogy Bryan Johnson’s post that his genome was of no use, and Anne Wojcicki’s response Francis Collins’s promise that genomes would guide blood pressure pills Zubin’s factor V Leiden and prothrombin findings, and what a genome did and didn’t tell him Why reading DNA like letters in a book is the wrong metaphor, and the Lego exhibit analogy Craig Venter’s genome talk and his “we can tell you when you will die” pitch Bryan Johnson’s changing positions, and what he eats Cheese fries, GERD, and a Dallas talk that felt like the whole room was talking Pain providers, opioids, the Sacklers, and the overcorrection that followed The parallel with SSRIs and the dilemma of taking people off a drug they shouldn’t have started A reported 40% rate of pancreatic cysts on MRI, IPMN, and the scan industrial complex Jalen Hurts’s blood clots: cleats to the calf, a long flight, and Virchow’s triad Lupus anticoagulant, factor V Leiden, and oral contraceptives Zubin’s daughter’s factor V Leiden and whether she can take the pill Goldfinger, a Scooby-Doo clip, and how standards have changed Next week’s topics and a plug to watch the Holmes documentary Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 ora
  • Nobel Prize Snubs, AI Medicine, Brain Death, SSRIs

    Nobel Prize Snubs, AI Medicine, Brain Death, SSRIs
    Oct 9 2026
    AI gave Zubin hair in our thumbnail...we truly are at End Times 😁 It's VPZD Ep. 45, originally streamed LIVE on YouTube. Chronological topic list Shout out to Dentalica, the Metallica cover band of dentists Follow up on the failed execution and whether healthcare professionals should take part in executions Firing squad and livestreamed executions as a case for the state owning its violence Childhood abuse, fetal alcohol syndrome, and whether crime is a medical problem or a moral one A bilingual doctor barred from speaking Spanish to her patient after failing a hospital proficiency test Nobel Prize snubs in optogenetics, including Ed Boyden, Feng Zhang, and the Wayne State researcher Rosalind Franklin, narrative, and why credit in science is so messy Why science is full of forced moves while art is not, and what that means for AI Clinical breakthroughs like Gleevec that never win Nobels Political Nobels, Obama, and Bob Dylan skipping the ceremony Academic AI studies that are outdated by publication, plus a Lancet “phase one” chatbot trial with no control arm AI models guessing Trump’s IQ and the case that the voting booth is the health check for politicians Why Zubin doesn’t vote, and the billionaire tax The seven levels of wealth and the arc from Rolex to no watch NYU’s three-year medical school and the cherry-picked comparison groups Zubin’s fourth year of medical school and finishing Berkeley in three years Reforming medical training from college through the extra fellowship year Teaching critical thinking over memorization as the line between charlatan and expert blurs Zeke Emanuel’s Eat Your Ice Cream, reverse causality, and confounding in observational studies The descriptive versus prescriptive fallacy in medicine and spiritual awakening Counseling cancer patients about alcohol SSRIs, RFK Jr., withdrawal, and why long-term data can’t separate benefit from dependence Brain zaps and SSRIs in awakening circles Vinay’s accidental decaf month and the nicotine gum trend Brain death, advance directives, and who you’d trust to pull the plug Moral anguish, organ and cadaveric nerve consent, and an ICU nurse’s perspective Airplane rules, annual PPD testing, and the absurdity of medical bureaucracy Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 ora e 11 min
  • Lethal Injection Ethics, Meditation Dangers, GRAIL Cancer Screening

    Lethal Injection Ethics, Meditation Dangers, GRAIL Cancer Screening
    Oct 4 2026
    Should we be medicalizing state-sanctioned executions? Is meditation actually safe? Do liquid biopsies save lives? EASY QUESTIONS ONE AND ALL 😂 Originally streamed ⁠⁠⁠⁠LIVE on YouTube⁠⁠⁠⁠! (#44) In this episode, we talked liquid biopsies for multi-cancer screening, the evidence behind recent blood test trials, and the risks of false positives and overdiagnosis. We dove into meditation’s possible benefits and harms, including anxiety, dissociation, and psychosis, as well as concerns about using it as a productivity tool. Finally, we hit physician involvement in state executions and the ethics of lethal injection, along with honest conversations about cancer prognosis and goals of care. ⁠⁠⁠⁠⁠Dr. Prasad's "Plenary Session" podcast.⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Dr. Damania's "ZDoggMD Show" podcast.⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠More on Vinay.⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠More on Zubin. Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 ora e 35 min
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