Joining Pat from Ukraine, Emmanuelle Chaze of France 24 describes the mood in Kyiv as power cuts become “incessant”, winter approaches, and trust in Washington hits crisis levels.

Pat is joined by Craig Hughes, Political Editor of the Irish Daily Mail to unpack the biggest political and public-interest stories making headlines.

Pat speaks to Sall Grover, founder of 'Giggle for Girls' - an app designed as a women-only online community and support network that was taken offline after sustained controversy and legal pressure. Sall outlines the events that led to the Tickle v. Giggle legal battle, the role of the Australian Human Rights Commission, and what the court ultimately decided about sex, gender identity, and access to women-only spaces.

Pat explores 200 years of the Coombe Hospital with Dr. Daryl Hendley Rooney, Curator and Senior Management member at the Little Museum of Dublin, as a new exhibition tells the story of one of the city’s most enduring institutions.

Pat is joined by chef, author and TV presenter Mark Moriarty to talk about his brand new book 'Everyday Delicious', a brand-new baby, and his first-ever restaurant.

Pat Kenny is joined in studio by David Hare, whose TV series and new book 'Legacy' shine a light on 32 of Ireland’s National Historic Properties in the care of the OPW. From Derrynane House and Daniel O’Connell’s fateful duel, to how Áras an Uachtaráin nearly didn’t survive the early years of the State, David explains what makes these buildings such good-value, must-see parts of our heritage.

Pat is joined by journalist Paul Cullen to trace the long, bruising saga of the National Children’s Hospital - a project first priced at €650 million and now estimated at well over €2.2 billion, with more rises likely. Drawing on his new book, Billion Dollar Baby, Cullen explains how decades of rivalry between Dublin’s children’s hospitals, a tortuous site-selection process, and planning missteps helped turn a once-unifying healthcare ambition into one of the State’s most troubled public builds.

Pat Kenny is joined by Prof Luke O’Neill to unpack two striking breakthroughs in brain science, starting with the Nobel Prize-winning technology that uses light to switch neurons on and off. From an algae protein to moving a mouse’s whiskers with a beam of light, they explore how this tool could transform how we study the living brain — and what it might mean for restoring sight or even tackling epilepsy. They also discuss the unsettling-but-promising work of growing human brain tissue from skin cells and wiring it into a mouse brain, opening new ways to study conditions like cerebral palsy.