From April 16, 1998: Author Wess Roberts discusses his book, Protect Your Achilles Heel, and the connection between behavior and intention. He explains the difference between behavior patterns and character flaws, the number one problem in relationships and the importance of selflessness. Oprah also talks to audience members about their biggest flaws.

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From April 20, 1998: Oprah talks to mothers who are making preparations for family after their deaths. New Zealand mother Tobi Mills opens up about placing a newspaper ad seeking a new family for her 10-year-old twins as she undergoes treatment for liver cancer. Erin Kramp shares motherly advice in videos to her daughter and husband while fighting breast cancer. Rose and Al Malavolti adopted eight children from a mother who was suffering from a terminal illness. (Erin Kramp passed away on October 31, 1998; her daughter was 6 years old. Tobi Mills also passed away in 1998.)

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From April 5, 2007: Oprah talks to parents and siblings of children on the autism spectrum about how this condition affects their lives. Dr. Anshu Batra, a developmental-behavioral pediatric specialist, discusses the three behavioral deficits that define autism, possible causes and early warning signs. Dr. Batra also opens up about the symptoms of her own autistic children and shares coping strategies parents can put in place.

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