Episodi

  • Universal Medical Intelligence: OpenAI's Plan to Elevate Human Health, with Karan Singhal

    Universal Medical Intelligence: OpenAI's Plan to Elevate Human Health, with Karan Singhal
    Feb 25 2026
    Karan Singhal, Head of Health AI at OpenAI, explains how ChatGPT Health is achieving attending-physician-level performance and already serving hundreds of millions of users. He details how OpenAI works with over 250 doctors, built the 49,000-criteria HealthBench evaluation, and ran one of the first randomized trials of AI copilots in clinical care. The conversation explores privacy and safety safeguards, medical multimodality, N-of-1 treatment plans, and how AI could become a standard part of global medical practice. Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot LINKS: modeling human wellness Sponsors: Claude: Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week 4 at https://serval.com/cognitive Framer: Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai CHAPTERS: (00:00) About the Episode (06:11) Cancer story and mission (11:46) Designing safe health AI (Part 1) (17:49) Sponsors: Claude | Serval (21:09) Designing safe health AI (Part 2) (26:48) Uncertainty, HealthBench and robustness (Part 1) (30:23) Sponsors: Framer | Tasklet (32:50) Uncertainty, HealthBench and robustness (Part 2) (38:11) Chain-of-thought and evaluation (46:49) Real-world performance and frontiers (55:35) Multimodal data and science (01:05:36) Personalization, privacy and monitoring (01:15:47) Models, data and incentives (01:29:31) Doctor adoption and workflows (01:38:13) Scalable oversight and alignment (01:51:06) Move 37 and future (02:00:50) Episode Outro (02:03:06) Outro PRODUCED BY: https://aipodcast.ing
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    2 ore e 1 min
  • Intelligence with Everyone: RL @ MiniMax, with Olive Song, from AIE NYC & Inference by Turing Post

    Intelligence with Everyone: RL @ MiniMax, with Olive Song, from AIE NYC & Inference by Turing Post
    Feb 22 2026
    Olive Song from MiniMax shares how her team trains the M series frontier open-weight models using reinforcement learning, tight product feedback loops, and systematic environment perturbations. This crossover episode weaves together her AI Engineer Conference talk and an in-depth interview from the Inference podcast. Listeners will learn about interleaved thinking for long-horizon agentic tasks, fighting reward hacking, and why they moved RL training to FP32 precision. Olive also offers a candid look at debugging real-world LLM failures and how MiniMax uses AI agents to track the fast-moving AI landscape. Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot LINKS: Conference Talk (AI Engineer, Dec 2025) – https://www.youtube.com/watch?v=lY1iFbDPRlwInterview (Turing Post, Jan 2026) – https://www.youtube.com/watch?v=GkUMqWeHn40 Sponsors: Claude: Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai CHAPTERS: (00:00) About the Episode (04:15) Minimax M2 presentation (Part 1) (17:59) Sponsors: Claude | Tasklet (21:22) Minimax M2 presentation (Part 2) (21:26) Research life and culture (26:27) Alignment, safety and feedback (32:01) Long-horizon coding agents (35:57) Open models and evaluation (43:29) M2.2 and researcher goals (48:16) Continual learning and AGI (52:58) Closing musical summary (55:49) Outro PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk
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    55 min
  • Mathematical Superintelligence: Harmonic's Vlad Tenev & Tudor Achim on IMO Gold & Theories of Everything

    Mathematical Superintelligence: Harmonic's Vlad Tenev & Tudor Achim on IMO Gold & Theories of Everything
    Feb 18 2026
    Vlad Tenev and Tudor Achim from Harmonic explain how they built Aristotle, an AI system that reaches International Mathematical Olympiad gold-medal performance using formally verified Lean proofs. They unpack the architecture behind mathematical superintelligence, including Monte Carlo Tree Search, lemma guessing, and specialized geometry modules. The conversation explores how verifiable reasoning could harden mission-critical software, reshape mathematical practice, and lead to trustworthy superintelligent systems by 2030. Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot Sponsors: Claude: Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at https://claude.ai/tcr Framer: Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai CHAPTERS: (00:00) About the Episode (04:58) Math as reasoning (Part 1) (15:22) Sponsors: Claude | Framer (18:51) Math as reasoning (Part 2) (18:51) Inside the Lean language (27:51) Lean intuition and MathLib (Part 1) (34:08) Sponsors: Blitzy | Tasklet (37:08) Lean intuition and MathLib (Part 2) (38:47) Inside Aristotle's architecture (48:33) Scope, boundaries, and applications (54:37) Training, taste, and interpretability (01:08:18) Formal math and software (01:16:50) Limits, entropy, and roadmap (01:25:24) 2030 vision and safety (01:33:38) Outro PRODUCED BY: https://aipodcast.ing
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    1 ora e 31 min
  • Approaching the AI Event Horizon? Part 2, w/ Abhi Mahajan, Helen Toner, Jeremie Harris, @8teAPi

    Approaching the AI Event Horizon? Part 2, w/ Abhi Mahajan, Helen Toner, Jeremie Harris, @8teAPi
    Feb 14 2026
    Abhi Mahajan (@owlposting) explains how AI is reshaping biology and medicine, including foundation models to predict cancer treatment response and why he’s both skeptical and optimistic about current results. Helen Toner unpacks CSET’s “When AI Builds AI” report and why automated AI R&D is a major source of strategic surprise. Jeremie Harris then explores our lack of control over superhuman AI systems, fragile US–China coordination, and how to maintain situational awareness in a rapidly shifting landscape. Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://recipes.granola.ai/r/4c1a6b10-5ac5-4920-884c-4fd606aa4f53 LINKS: Abhi Mahajan's Owl Posting site Heuristics for lab robotics article Deep Research on Noetik AI Sponsors: GovAI: GovAI was founded ten years ago on the belief that AI would end up transforming our world. Ten years later, the organization is at the forefront of trying to help decision-makers in government and industry navigate the transition to advanced AI. GovAI is now hiring Research Scholars (one-year positions for those transitioning into AI policy) and Research Fellows (longer-term roles for experienced researchers). Both roles offer significant freedom to pursue policy research, advise decision-makers, or launch new initiatives. Applications close 15 February 2026. Apply at: https://www.governance.ai/opportunities Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive PRODUCED BY: https://aipodcast.ing
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    2 ore e 23 min
  • Approaching the AI Event Horizon? Part 1, w/ James Zou, Sam Hammond, Shoshannah Tekofsky, @8teAPi

    Approaching the AI Event Horizon? Part 1, w/ James Zou, Sam Hammond, Shoshannah Tekofsky, @8teAPi
    Feb 13 2026
    Part 1 of this live special dives into AI for Science, U.S. AI policy, and the behavior of AI agents in open-ended environments. James Zou explains how interpretability and virtual labs of AI agents can accelerate scientific discovery. Sam Hammond assesses the Biden administration’s AI policy, U.S.–Gulf AI deals, and the odds current AIs are conscious. Shoshannah Tekofsky shares insights from studying agent performance and emergent behavior in the AI Village. Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://recipes.granola.ai/r/4c1a6b10-5ac5-4920-884c-4fd606aa4f53 LINKS: Model human wellness project doc AI Village 2025 findings report Sponsors: GovAI: GovAI was founded ten years ago on the belief that AI would end up transforming our world. Ten years later, the organization is at the forefront of trying to help decision-makers in government and industry navigate the transition to advanced AI. GovAI is now hiring Research Scholars (one-year positions for those transitioning into AI policy) and Research Fellows (longer-term roles for experienced researchers). Both roles offer significant freedom to pursue policy research, advise decision-makers, or launch new initiatives. Applications close 15 February 2026. Apply at: https://www.governance.ai/opportunities Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive PRODUCED BY: https://aipodcast.ing
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    1 ora e 32 min
  • AGI-Pilled Cyber Defense: Automating Digital Forensics w/ Asymmetric Security Founder Alexis Carlier

    AGI-Pilled Cyber Defense: Automating Digital Forensics w/ Asymmetric Security Founder Alexis Carlier
    Feb 8 2026
    Alexis Carlier, founder of Asymmetric Security, explains how assuming AGI-level intelligent labor should transform cybersecurity from reactive triage to proactive, continuous digital forensics. He breaks down today’s threat landscape—from “spray and pray” cybercrime to nation-state IP theft and North Korean “remote workers.” The conversation explores Asymmetric’s AI agents for deep investigations, their services-first approach to business email compromise, and how specialized digital forensics may differentially accelerate defensive AI capabilities. Use the Granola Recipe Nathan relies on to identify blind spots across conversations, AI research, and decisions: https://bit.ly/granolablindspot Sponsors: GovAI: GovAI was founded ten years ago on the belief that AI would end up transforming our world. Ten years later, the organization is at the forefront of trying to help decision-makers in government and industry navigate the transition to advanced AI. GovAI is now hiring Research Scholars (one-year positions for those transitioning into AI policy) and Research Fellows (longer-term roles for experienced researchers). Both roles offer significant freedom to pursue policy research, advise decision-makers, or launch new initiatives. Applications close 22 February 2026. Apply at: https://www.governance.ai/opportunities Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Claude Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at ⁠⁠https://claude.ai/tcr⁠ CHAPTERS: (00:00) About the Episode (04:20) Defining AGI and jaggedness (12:27) Modern cyber threat landscape (Part 1) (19:10) Sponsors: GovAI | Blitzy (22:17) Modern cyber threat landscape (Part 2) (29:58) AI-powered cyber defense (Part 1) (33:31) Sponsors: Serval | Tasklet (36:20) AI-powered cyber defense (Part 2) (42:20) Inside digital forensics workflows (51:52) Bootstrapping AI cyber defense (59:17) Shaping the capability frontier (01:08:44) Future of automated forensics (01:17:59) Outro PRODUCED BY: https://aipodcast.ing
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    1 ora e 16 min
  • Infinite Code Context: AI Coding at Enterprise Scale w/ Blitzy CEO Brian Elliott & CTO Sid Pardeshi

    Infinite Code Context: AI Coding at Enterprise Scale w/ Blitzy CEO Brian Elliott & CTO Sid Pardeshi
    Feb 5 2026
    Blitzy founders Brian and Sid break down how their “infinite code context” system lets AI autonomously complete over 80% of major enterprise software projects in days. They dive into their dynamic agent architecture, how they choose and cross-check different models, and why they prioritize advances in AI memory over fine-tuning. The conversation also covers their 20¢/line pricing model, the path to 99%+ autonomous project completion, and what this all means for the future software engineering job market. Sponsors: Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive CHAPTERS: (00:00) About the Episode (03:02) AGI effects without AGI (07:07) Domain-specific context engineering (16:54) Dynamic harness and evals (Part 1) (17:00) Sponsors: Blitzy | Tasklet (20:00) Dynamic harness and evals (Part 2) (30:42) Graphs, RAG, and memory (Part 1) (30:49) Sponsor: Serval (32:26) Graphs, RAG, and memory (Part 2) (41:17) Model zoo and memory (50:07) Planning, scaling, and parallelism (56:13) Pricing, onboarding, and autonomy (01:04:24) Closing the last 20% (01:12:34) Strange behaviors and judges (01:22:23) Reasoning budgets and autonomy (01:33:36) Fine-tuning, benchmarks, and training (01:42:31) Securing AI-generated code (01:49:52) Future of software work (01:57:05) Outro PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk
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    1 ora e 57 min
  • The AI-Powered Biohub: Why Mark Zuckerberg & Priscilla Chan are Investing in Data, from Latent.Space

    The AI-Powered Biohub: Why Mark Zuckerberg & Priscilla Chan are Investing in Data, from Latent.Space
    Feb 1 2026
    This crossover episode from the Latent Space podcast features Mark Zuckerberg and Priscilla Chan on the 10-year anniversary of the Chan Zuckerberg Initiative and their expanded Biohub vision. They discuss how a “Frontier Biology Lab” working in sync with a “Frontier AI Lab” could enable breakthroughs like a Virtual Cell and true N-of-1 precision medicine. The conversation covers the acquisition of Evolutionary Scale and ESM3, new biological data collection at scale, and how AI-powered biology might transform drug discovery and disease prevention. Sponsors: Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Framer: Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai CHAPTERS: (00:00) About the Episode (04:27) CZI origins and focus (08:29) Why tools over cures (14:43) Virtual cells and imaging (Part 1) (20:19) Sponsors: Blitzy | Framer (23:24) Virtual cells and imaging (Part 2) (25:22) Data diversity and grounding (32:30) Evaluating models and Biohub (Part 1) (37:53) Sponsors: Serval | Tasklet (40:42) Evaluating models and Biohub (Part 2) (41:06) Future healthcare and aging (53:39) Modeling scales and immunity (58:53) Timelines, data, and collaboration (01:04:01) Outro PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://www.cognitiverevolution.ai Twitter (Podcast): https://x.com/cogrev_podcast Twitter (Nathan): https://x.com/labenz LinkedIn: https://linkedin.com/in/nathanlabenz/ Youtube: https://youtube.com/@CognitiveRevolutionPodcast Apple: https://podcasts.apple.com/de/podcast/the-cognitive-revolution-ai-builders-researchers-and/id1669813431 Spotify: https://open.spotify.com/show/6yHyok3M3BjqzR0VB5MSyk
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    1 ora e 2 min