Can platelet-rich plasma improve outcomes in veterinary dental patients?

In this episode of Sit. Stay. Learn., Dr. Adrienne Wright reviews a recent study evaluating autologous PRP as an adjunct to routine dental treatment in small-breed dogs with stage 2–3 periodontitis.

The study compared dental cleaning alone with dental cleaning plus PRP injections. After 30 days, the PRP group showed improvements in gingival inflammation, periodontal pocket depth, disease stage, and horizontal bone loss measurements.

Dr. Wright breaks down the study design, the results, PRP’s anti-inflammatory and antimicrobial properties, and one important detail: the researchers used non-activated PRP.

Listen to Episode 12 to hear what the findings could mean for regenerative medicine in veterinary dentistry.

Can orthobiologics outperform steroids in equine osteoarthritis treatment?

In Episode 11 of Sit. Stay. Learn., Dr. Adrienne Wright reviews the 2020 paper “Effects of Autologous Conditioned Serum, Autologous Protein Solution, and Triamcinolone on Inflammatory and Catabolic Gene Expression in Equine Cartilage and Synovial Explants Treated with IL-1β in Co-culture” and breaks down how ACS, APS, and triamcinolone compare in an inflamed joint model.

In this episode, she covers: • what autologous conditioned serum (ACS) and autologous protein solution (APS) are • how these orthobiologics compare to triamcinolone • what the study found about inflammatory gene expression • why PGE2 reduction matters in equine OA • and what this could mean for managing lameness and joint disease in horses

If you’re interested in equine sports medicine, orthobiologics, regenerative medicine, or practical veterinary research, this episode offers a quick and useful breakdown of the science.

Reach out to Dr. Adrienne Wright at adrienne@ardentanimalhealth.com with any questions, to continue the conversation, or to suggest a study you’d like her to review next.

Cancer affects far too many dogs, and better treatment options are urgently needed. In Episode 10 of Sit. Stay. Learn., Dr. Adrienne Wright reviews the paper “Autologous Cancer Vaccines: A Precision Immunotherapy Strategy for Veterinary Cancer Patients” and explains how autologous cancer vaccines may offer a more personalized way to fight cancer in dogs. This episode covers tumor antigens, neoantigens, checkpoint inhibitors, and why veterinary immunotherapy is an area to watch.