RHR: Can You Reverse Your Biological Age? copertina

RHR: Can You Reverse Your Biological Age?

RHR: Can You Reverse Your Biological Age?

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In this episode of Revolution Health Radio, Chris Kresser explores what biological age really means and examines the research behind today's most popular longevity claims. He explains how epigenetic clocks and DNA methylation are used to estimate biological aging, why these tests may be less precise for individuals than they appear, and what studies like the CALERIE trial tell us about slowing the aging process. You'll also learn why reversing a biological age number isn't the same as reversing aging, and how meaningful improvements in muscle strength, cognition, metabolic health, and physical function can be achieved at virtually any age. He also offers a practical framework to build a strong foundation of sleep, nutrition, movement, stress management, connection, and purpose before investing in advanced longevity technologies or supplements. In this episode we discuss: What biological age means and why biological-age tests can be misleadingWhy slowing aging is different from reversing agingHow aging-related changes in muscle, strength, cognition, and physical function can be meaningfully improvedThe role of sleep, movement, nutrition, stress management, connection, and purpose in healthy agingWhy foundational lifestyle habits should form the base of your longevity pyramidWhere interventions such as sauna, cold exposure, red-light therapy, and other advanced tools fit into a sensible longevity strategyWhich markers may be more actionable measures of healthy aging than a single biological-age scoreWhat the research says about multivitamins, omega-3s, spermidine, ergothioneine, and other emerging longevity compounds Show notes: "Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial" by Baker, L.D., et al."Prospective study of dietary mushroom intake and risk of mortality: Results from continuous National Health and Nutrition Examination Survey (NHANES) 2003–2014 and a meta-analysis" by Ba, D.M., et al."DunedinPACE, a DNA methylation biomarker of the pace of aging" by Belsky, D.W., et al."Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial" by Bischoff-Ferrari, H.A., et al."Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart Study" by Harris, W.S., et al."Impact of healthy lifestyle factors on life expectancies in the US population" by Li, Y., et al."Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS" by Vyas, C.M., et al."Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial" by Waziry, R., et al."The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial" by Wirth, M., et al."Multivitamin supplementation improves memory in older adults: A randomized clinical trial" by Yeung, L.-K., et al.If you'd like to ask a question for Chris to answer in a future episode, submit it hereFollow Chris on Instagram or Facebook Add back in what the modern world has crowded out and feel and perform your best with Adapt Naturals supplements. Learn more and place your order at AdaptNaturals.com. If you appreciate the show and want to help create a healthier and happier world, consider leaving a review!
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