What if healthcare focused on keeping us healthy instead of waiting for us to become sick?

In this episode, I sit down with Dr. Leroy Hood—a pioneering biologist, co-founder of the Institute for Systems Biology, and one of the visionaries behind modern genomics—to explore how science is transforming the future of medicine.

We discuss the origins of systems biology, the evolution of Predictive, Preventive, Personalized, and Participatory (P4) medicine, and why understanding the human phenome may be just as important as understanding the genome. Dr. Hood also shares his vision for Phenome Health, the role of artificial intelligence in healthcare, the future of aging, and how understanding our biology may reshape what it means to be human.

Whether you're interested in medicine, biotechnology, artificial intelligence, or the future of human health, this conversation offers a thought-provoking look at where healthcare is headed next.

The future of medicine is arriving faster than most people realize. This season, InfoPoint explores what's coming: AI-driven diagnostics, biology we can engineer, and a shift from treating disease to catching it before it starts. Host Isha Joshi talks with the researchers pushing these fields forward, including genomics pioneer Dr. Leroy Hood and gut-brain scientist Dr. Sarkis Mazmanian, among others working at the edges of healthcare and science. Each episode unpacks one scientific frontier — and the harder question sitting just behind it: how far should this go?

Dr. Anne Wylie never planned to fall in love with microbiology, but that unexpected passion led her to create SalivaDirect, the low-cost, saliva-based COVID-19 test that reshaped diagnostic testing during the pandemic. In this episode, she shares her winding path from New Zealand to Amsterdam to Yale, the frantic weekend SalivaDirect went live with the FDA, and what she's learned about mentorship, resilience, and following what gives you joy — even when it means changing course.