Key Subjects with Timestamps:

1. Checking for Drug-Drug Interactions with Cannabis (32:26.998 - 34:56.588)

- Considerations before shifting a patient from mainstream medications (SSRIs or opioids) to plant-based therapy.

- Checking for drug interactions using online drug interaction checkers like Medscape.

- THC and CBD are metabolized by cytochrome P450 enzymes, leading to potential interactions with certain medications.

- High-risk medications like tacrolimus and clopidogrel may have significant interactions with CBD.

- Considerations for using cannabis in combination with other medications and assessing potential catastrophic consequences.

2. Drug-Drug Interaction Check for Cannabis (37:45.132 - 38:50.432)

- Drug interaction checkers are useful and effective for cannabis as well, especially with the data from Epidiolex and Sativex trials.

- Clinical relevance of interactions with cannabis is generally low, except at very high doses, particularly in the case of CBD.

3. Identifying Patients Who May Benefit from Cannabis (39:11.294)

- For patients not responding well to their current medication paradigm, there might be an indication that cannabis could be a potential treatment option.

Please note that the timestamps are approximate and may vary slightly depending on the audio recording.