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How This Is Building Me

How This Is Building Me

Di: How This Is Building Me
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A proposito di questo titolo

 World-renowned oncologist D. Ross Camidge, MD, PhD, sits down with guests to discuss the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences. Scienza
Episodi
  • S2 Ep1: How Community Oncology Experience Built the Foundation for a Dedicated Phase 1 Research Program: With D. Ross Camidge, MD, PhD; and Justin Call, MD

    S2 Ep1: How Community Oncology Experience Built the Foundation for a Dedicated Phase 1 Research Program: With D. Ross Camidge, MD, PhD; and Justin Call, MD
    Jan 21 2026

    How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.

    In this episode, Dr Camidge sat down with Justin Call, MD. Dr Call is a medical oncologist and hematologist at Utah Cancer Specialists in South Jordan.

    Dr Call explained that he has taken a unique professional path, transitioning from practicing as a general community oncologist to becoming a full-time phase 1 principal investigator within a community practice setting. He explained that he grew up in Salt Lake City, Utah in a family of educators and accountants, though he was heavily influenced by several uncles who were physicians, including one oncologist. After completing his medical training at the University of Colorado, he chose community oncology over academia because he wanted to remain a generalist who could treat all tumor types rather than being restricted to a specific disease group. A formative rotation at Rocky Mountain Cancer Centers solidified this desire, as Dr Call noted he was impressed by the deep knowledge required to treat various cancers and the positive atmosphere of outpatient care.

    Dr Call emphasized that his personal life significantly influenced his career choices. His son, Trevor, was diagnosed with autism at 18 months old. This diagnosis eventually led the family to move from a rural practice in Petoskey, Michigan, back to Utah to access better support services and be closer to family. His son’s experience also inspired Call's wife to earn a master’s degree in special education.

    Upon returning to Utah Cancer Specialists, Dr Call initially participated in phase 3 trials. However, he retained an interest in early-phase research from his fellowship days. In 2016, he began building a boutique phase 1 program, initially starting with just 2 hours of dedicated time per week. In 2020, his practice partnered with START (South Texas Accelerated Research Therapeutics) to launch a dedicated, full-time, community-based phase 1 program. Dr Call noted that this model is rare because phase 1 trials are highly competitive and require specialized infrastructure, such as dedicated pharmacists, coordinators, and equipment for processing pharmacokinetic samples.
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    1 ora e 13 min
  • 50: How Biostatistics Expertise Led to a Career of Propelling Ethical Clinical Trial Design: D. Ross Camidge, MD, PhD; and Tom Fleming, PhD

    50: How Biostatistics Expertise Led to a Career of Propelling Ethical Clinical Trial Design: D. Ross Camidge, MD, PhD; and Tom Fleming, PhD
    Dec 24 2025
    How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.

    In this episode, Dr Camidge sat down with Tom Fleming, PhD, a professor of biostatistics at the University of Washington School of Public Health in Seattle.

    Drs Camidge and Fleming discussed how Fleming's interest in biostatistics led to a multifaceted career in clinical trial design and analysis. Fleming pursued a PhD in math and statistics and spent his early career learning to bridge quantitative sciences with clinical medicine, working on landmark trials for adjuvant colon cancer and debunking megadoses of Vitamin C as a cancer treatment.

    A primary focus of Fleming’s career was pioneering the use of Data Monitoring Committees (DMCs) in oncology research to safeguard patient interests and trial integrity, later convincing organizations like SWOG to adopt DMCs to prevent premature data releases and biases. He also co-developed the O'Brien-Fleming monitoring boundary, a statistical framework that allows trials to stop early for efficacy only when the signal is undeniably compelling, thereby protecting scientific rigor.

    After moving to the University of Washington, Fleming expanded his focus into infectious diseases. He led international efforts that revolutionized HIV/AIDS prevention, including demonstrating a reduction in heterosexual transmission of the disease through antiretrovirals and significantly reducing mother-to-child transmission in resource-limited settings.

    Fleming remains a staunch advocate for confirmatory trials and the use of overall survival as the "gold standard" end point, often expressing skepticism toward surrogate biomarkers like progression-free survival. In the episode, he emphasized that rigorous science is possible even in the most challenging environments, provided there is a commitment to clinical equipoise and high patient retention. Outside of his professional life, Fleming prioritizes family and coaches youth soccer teams, reflecting his belief in the power of collaboration.
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    1 ora e 11 min
  • 49: How Compelling Communication Makes Early Cancer Detection Part of Everyday Life: With D. Ross Camidge, MD, PhD; and Keith Singer

    49: How Compelling Communication Makes Early Cancer Detection Part of Everyday Life: With D. Ross Camidge, MD, PhD; and Keith Singer
    Dec 10 2025
    How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.

    In this episode, Dr Camidge sat down with Keith Singer, the founder and executive director of Catch It In Time.

    Camidge and Singer discussed how Singer's background in broadcasting and cable television has led to a career in promoting cancer awareness. Although Singer initially wanted to be an astronaut, a decline in aerospace engineering jobs during the 1970s and a love for the technical side of high school theater led Singer toward television. He left college early and started his career in Cincinnati, first running a boom microphone and later directing newscasts. Singer explained the career hurdles he faced, noting that they led to opportunities for him to hone his skills and exercise creative freedom.

    In the mid-1980s, a project involving a new pacemaker sparked Singer's interest in using video for health care education. This fascination led him to co-create an innovative platform that broadcast medical programming for physician continuing medical education. Driven by seeing friends and family struggle with cancer, Singer founded the nonprofit Catch It In Time in 2011. His key communication strategy is that cancer should be the supporting actor, not the lead, allowing stories to appeal to targeted audiences based on their hobbies or professions, with cancer awareness as the secondary message.

    Catch It In Time is currently developing The User's Guide to Oncology, a software-based program that uses gaming technology to guide patients with lung cancer, providing essential information to help them have better conversations with their care teams. Singer stressed the importance of short video content for garnering views for this type of content.

    Notably, Catch It In Time recently produced a song titled "Breathe Again" by Lilliana De Los Reyes. "Breathe Again" can be found on all major streaming platforms, and all proceeds are dedicated to cancer awareness and research.
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    1 ora e 4 min
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