GLP-1 Medications and Weight Cycling: What Patients Need to Know
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GLP-1 Medications and Weight Cycling: What Patients Need to Know
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Why do GLP-1 medications seem to work great the first time—but not as well when you stop and restart them?
In this episode of The Medical Weight Loss Show, Dr. Andrea Walker, FNP, IFBB Pro, breaks down why repeatedly going on and off GLP-1 medications can actually make weight loss harder over time. Drawing from years of clinical experience, Dr. Walker explains the science behind metabolic adaptation, hormone regulation, receptor response, and why appetite, cravings, and weight regain often feel worse after stopping.
You’ll learn:
Why GLP-1s are difficult to manage without a long-term plan
Why weight regain happens so quickly after stopping
Why GLP-1 medications may take longer to work—or feel less effective—when restarted
How muscle loss, insulin resistance, and stress impact results
Why obesity should be treated as a chronic medical condition, not a short-term fix
This episode is educational, honest, and empowering—without judgment or shame. Whether you’re currently on a GLP-1, considering stopping, or thinking about restarting, this conversation will help you understand what your body is actually doing and how to work with it instead of against it.