In this episode of Out of Network, Dr. Ryon Parker and Dr. Rishi Seth dive deep into the explosive world of GLP-1 medications—exploring the realities of semaglutide, tirzepatide, Ozempic, Wegovy, and Zepbound. With a projected $200 billion market by 2029, these drugs have transformed weight management, but they've also created chaos in the healthcare landscape. From med spa injections to proper medical supervision, this conversation sheds light on what safe GLP-1 treatment should actually look like.

What You'll Learn

• The difference between proper medical weight loss programs and dangerous "syringe-in-a-fridge" clinics
• Why tirzepatide (Mounjaro/Zepbound) outperforms semaglutide (Ozempic) in most patients
• Real strategies for patients who plateau or don't respond to GLP-1 medications
• Insurance coverage realities and the new $50/month Medicare pricing
• Serious side effects to watch for, including pancreatitis and gallbladder issues

Timestamps

• 00:00 – Introduction: The $200 billion GLP-1 economy
• 03:15 – Wild West of GLP-1 prescribing: Med spas and strip mall clinics
• 10:42 – Proper patient screening and medical supervision
• 24:30 – Insurance coverage, pricing, and access issues
• 32:00 – Tirzepatide vs. Semaglutide: Which is better?
• 42:55 – The future of GLP-1s and closing thoughts

Connect with Out of Network:
🌐 Website: https://www.outofnetworkpod.com/
📱 Instagram: https://www.instagram.com/outofnetworkpodcast/
▶️ YouTube: https://www.youtube.com/@OutofNetworkPodcast
🎵 TikTok: https://www.tiktok.com/@outofnetworkpodcast

Connect with the Hosts:
Dr. Ryon Parker → https://www.instagram.com/dr.ryonparker/
Parker Medical: https://parkermedical.org/
Dr. Rishi Seth → https://www.instagram.com/drrishiseth/
Seth Premiere Medical: https://sethmedical.com/

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🎙 About Out of Network
Out of Network is a bold, physician-led podcast hosted by Dr. Ryon Parker and Dr. Rishi Seth. Each week, they challenge the broken healthcare system and explore how medicine can be reimagined—through patient-first care, prevention, and real human stories.

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