From First Principles copertina

From First Principles

From First Principles

Di: Krishna Choudhary and Lester Nare
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From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.Krishna Choudhary and Lester Nare Scienza
  • FFP EP. 22 | Cloud9 Dark Matter Halo, Jellyfish Sleep, and String Theory Hidden in Nature
    Jan 20 2026

    Hosted by Lester Nare and Krishna Choudhary, this episode runs from the deep math of string theory to the biology of sleep—then out to a starless “ghost cloud” that may be a naked dark-matter halo. We open with a Nature paper showing that physical networks in nature (brains, blood vessels, fungal networks) appear to organize like energy-minimizing surfaces—spitting out the same branching rules you see in soap films and (surprisingly) in the mathematics behind string theory. Then we hit a neuroscience twist: even simple jellyfish need sleep—and the evidence points to sleep as a repair cycle for DNA damage. We close with Cloud9, a newly characterized, starless gas cloud that could be a rare “reionization-limited” RELHIC—potentially exposing a dark matter halo without the glare of stars.


    Summary

    • String theory… in your body? Why real-world transport networks converge toward minimal-energy geometry—and what that has to do with string-theory math and 120° branching angles.


    • Jellyfish need sleep (and it’s not optional): Evidence that sleep pressure tracks cellular stress and DNA damage repair—even in a brainless animal.


    • Cloud9: A nearby starless cloud that may be a dark matter halo in plain sight—plus what it implies about “missing” galaxies and the post-reionization universe.


    • The Rundown: iron asteroids, artificial metabolism (ReForm), scalable helper T-cells from stem cells, and NASA’s Pandora exoplanet mission.


    Show Notes

    • Physical networks / string-theory-like math (Nature)
    • Jellyfish sleep & DNA repair (Nature Communications)
    • Cloud9 (Astrophysical Journal Letters)
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    1 ora e 40 min
  • FFP EP. 21 | Roman Concrete, Brain “Cognitive Legos,” DeepSeek, and Econophysics
    Jan 12 2026

    Hosted by Lester Nare and Krishna Choudhary, this episode jumps from ancient engineering to modern AI and markets. We start with the newly uncovered Pompeii worksite that finally shows how Romans mixed their concrete — and why it “self-heals.” Then we pivot into a Princeton neuroscience idea that the brain builds complex thought like LEGO bricks (compositional neural subspaces). From there, we break down DeepSeek’s “manifold-constrained hyperconnections” as a stability mechanism for scaling deep nets. And we close with econophysics: a Physical Review Letters result arguing the square-root law of market impact is strictly universal across stocks and time.


    Summary

    • Roman concrete’s missing step — Pompeii evidence for “hot mixing,” lime clasts, and why cracks can heal themselves for millennia.
    • Cognitive LEGOs — a compositionality framework where brains reuse shared neural subspaces to assemble new tasks.
    • DeepSeek’s scaling trick — constraining hyperconnections to a stable manifold to avoid vanishing/exploding signals.
    • The universal market law — PRL evidence that price impact follows a square-root rule across stocks, traders, and decades.

    Show Notes

    • ⁠Roman Concrete (Pompeii worksite) — Nature Communications (2025)⁠
    • ⁠Hot Mixing & Lime Clasts — Science Advances (2023)⁠
    • ⁠Compositional Neural Subspaces (“Cognitive LEGOs”) — Nature (2025)⁠
    • ⁠mHC: Manifold-Constrained Hyper-Connections — arXiv⁠
    • ⁠Square-Root Law of Market Impact (Universality) — Physical Review Letters⁠
    • ⁠Artemis II Countdown Demonstration Test — NASA
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    1 ora e 59 min
  • FFP EP. 20 | The Physics Behind Fusion’s Biggest Problem (Season Finale)
    Dec 23 2025

    Hosted by Lester Nare and Krishna Choudhary, this Season Finale closes out Season 1 with a deep dive into the physics behind fusion’s biggest bottleneck: fast magnetic reconnection. We unpack why classic models predicted reconnection should be slow, why nature (and tokamaks) disagree, and how modern “plasmoid” reconnection helps explain solar flares, plasma instabilities, and the real engineering challenges fusion reactors face. Then we run a full Season 1 recap — our favorite episodes, biggest scientific moments, and the corrections and lessons we’re taking into Season 2.


    Summary

    • Fusion’s biggest problem — magnetic reconnection, why the Sweet–Parker model breaks down at scale, and how plasmoid instability enables fast reconnection.
    • From the Sun to tokamaks — how reconnection drives solar flares, space weather, and plasma confinement limits in fusion devices.
    • Season 1 leaderboard — our top episodes and the breakthroughs that stuck: astronomy, biology, AI, quantum, and the history of science.
    • Corrections + what’s next — what we fixed, what we learned, and how Season 2 evolves the format.
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    1 ora e 18 min
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