Learn fibrates (fibric acid derivatives)—fenofibrate and gemfibrozil—common triglyceride-lowering drugs for hypertriglyceridemia. In this lecture from This is Why, Dr. Busti will break down how fibrates (fenofibrate and gemfibrozil) work, when to use them, and the safety pearls you need for the patient with high triglycerides, which can lead to pancreatitis.

You’ll learn how to:
- Mechanism: PPAR-α activation → ↓ triglycerides (TG), ↓ VLDL, ↑ HDL
- Fenofibrate vs gemfibrozil: key differences that matter for practice questions
- Indications: managing high triglycerides (including reducing pancreatitis risk in severe TG)
- Adverse effects & monitoring: myopathy risk, LFTs, gallstones, and what to watch for
- Drug interactions: especially with statins (testable!)

The goal = make medical education easy and clinically relevant.

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#fibrates #fenofibrate #gemfibrozil #hypertriglyceridemia #busti

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.