Diagnosing Hemophagocytic Lymphohistiocytosis (HLH)
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Diagnosing Hemophagocytic Lymphohistiocytosis (HLH)
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Adam Narloch speaks with Dr Ashish Kumar and Dr Scott Canna to discuss the challenges involved with diagnosing and managing hemophagocytic lymphohistiocytosis (HLH). The discussion focuses on key considerations in HLH management, treatment goals, and clinical complexities involved in evaluating patients with HLH.
This video features expert clinician discussion and is intended for US healthcare professionals.
Chapters
0:00 - Why HLH Diagnosis Can Be Challenging
4:59 - Why Early and Accurate HLH Diagnosis Matters
10:10 - HLH Diagnostic Criteria and Clinical Workup
25:31 - Genetic Testing and Functional Assays for HLH
37:26 - Biomarkers in HLH Diagnosis: Ferritin, sCD25, and CXCL9
43:00 - HLH Disease Mimics and Differential Diagnosis
54:00 - HLH Guidelines: Limitations and Clinical Judgment
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