The US and Israel began striking targets across Iran, with President Donald Trump urging Iranians to overthrow the government in a conflict that threatens to spiral across the oil-rich Middle East.

“The hour for your freedom is at hand,” Trump said, addressing Iranians in a video posted on Truth Social on Saturday. “When we’re finished, take over your government. It will be yours to take. This will be probably your only chance for generations.”

The military campaign could be a defining moment for Trump, risking a drawn-out regional war that leads to a surge in energy prices and American casualties ahead of mid-term elections this year. Iran quickly responded by firing missiles on Israel and US bases around the region, and countries in the Persian Gulf closed their airspace.

Israel’s military said the campaign would target “dozens of military targets,” and Iran media reported strikes on defensive and civilian sites, including more than 50 people dead in a strike on a school in Hormozgan, in the south of the country. Several large explosions were reported in the capital, Tehran.
Bloomberg's David Gura and Christina Ruffini lead our team coverage in this instant reaction podcast.

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Bloomberg Daybreak Weekend with Host Nathan Hager take a look at some of the stories we'll be tracking in the coming week.

• In the US – a look ahead to the February jobs report, along with a focus on 3 stocks for the week ahead.
• In the UK – a look ahead to "Made in Europe" the tagline of a new scheme to rejuvenate Europe's defense, energy, and manufacturing sectors.
• In Asia – a look ahead to China PMI data.

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Business and finance news from the Asia-Pacific.

Japanese tech stocks showed mixed performance today, with the broader market experiencing modest movements and individual tech names displaying varied results. Also, a Tokyo inflation gauge eased to the slowest pace in more than a year as Prime Minister Sanae Takaichi's utility subsidies curbed household energy costs. We speak to Alice French, Bloomberg's Japan Stocks Reporter..

Plus - US and Iranian officials ended the latest round of nuclear talks in Geneva on Thursday by agreeing to reconvene as soon as next week, opening the door to further diplomacy even as President Donald Trump masses military forces in the region. With just days to go before Trump's deadline to reach an agreement, the two sides agreed to resume discussions at a technical level in Vienna. Oil pared gains given the prospect of more talks, though there was no public reaction from the US side, led by special envoy Steve Witkoff and Trump's son-in-law Jared Kushner. A person familiar with the US position said the Americans were leaving Geneva disappointed with the progress of the talks. Axios reported earlier that Kushner and Witkoff were disappointed by what they heard from Iranian officials in their morning session. We heard from Mara Rudman, Miller Center Practitioner Senior Fellow and Former US Deputy Envoy and Chief of Staff for the Office of the Special Envoy for Middle East Peace. She spoke to Bloomberg TV hosts Haidi Stroud-Watts and Shery Ahn on the Asia Trade.

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