A totally heartbreaking but uplifting story about family, loss and second chances.

Three years after Daniel was killed by a senseless act of violence, all his sisters have left of him are their memories - and responsibility for Daniel's mischievous dachshund John Thomas. Daniel donated his organs, his death facilitating life-saving miracles for other families, while his own loved ones struggle to come to terms with their devastating loss, each at a crossroads of her own.

It's been twelve years since film director Bridie had a hit, and while she's still invited to glitzy media events, nowadays it is as her successful actor husband's plus one.

Clare and her wife Sophie have been through four rounds of IVF and while Clare remains hopeful to keep trying, it may be at the cost of her marriage...

Conscientious Allison looks after everyone. Her younger siblings, her children and the many patients she treats in her job as Chief Obstetrician at a big teaching hospital. But who's looking out for Allison?

Emma is looking for love, but isn't having much luck on dates. And there's something she can't tell anyone, whether romantic prospect or even her family, about the real reason she quietly abandoned a musical career that she loved...

When Clare suggests that they try to make contact with the recipients of Daniel's organs to honour their brother, not everyone thinks it's a good idea. It's a heart-wrenching process, but will meeting those that their brother saved help to bring the sisters back together, or will old tensions and surfacing secrets splinter the fragile family ties forever?