In this episode, we sit down with Sarah Kennedy, Founder and CEO of Calocurb, to explore a radically different approach to appetite control rooted in real science, not willpower. With decades of leadership in nutrition and food science, Sarah breaks down how GLP-1s work, the downsides of chronic calorie restriction, and the key differences between synthetic drugs like semaglutide and natural GLP-1 stimulation. We dive into the history of bitters, digestion, and how Calocurb’s patented ingredient Amarasate® supports appetite regulation through the gut–brain axis. Sarah also shares compelling clinical trial results, insights on coming off GLP-1 drugs, and why under-eating—especially for women—can backfire hormonally. It’s a nuanced, empowering conversation about working with your biology to feel satisfied, nourished, and in control.

Founder and CEO of Calocurb, Sarah Kennedy shepherded years of scientific research and clinical trials to bring a revolutionary product to market. A veterinarian by training, with more than 20 years’ experience in dietary and animal nutrition, Sarah has held a number of CEO and senior executive positions in food and agriculture industries, at companies including Fonterra and Healtheries/Vitaco NZ. In 2010, at MIT, Sarah completed a Sloan Fellowship Program in Global Leadership and Innovation and has spent decades leading in health, nutrition and consumer products with executive roles at many, many companies.

Calocurb is a 100% natural appetite control supplement. Amarasate®, the patented active ingredient in Calocurb, was developed in New Zealand over 14 years and with $30m invested by Plant and Food Research, the largest NZ government-owned research institute.

SHOW NOTES:

0:40 Welcome to the show!

2:39 About Sarah Kennedy

3:54 Welcome her to the podcast!

5:04 What is a GLP-1?

7:27 Downside of calorie restriction

8:52 Natural vs synthetic GLP-1

13:41 Coming off of GLP-1s

14:56 Why it isn’t just willpower

18:07 History of bitters in the diet

20:12 Stimulating digestion & appetite suppression

23:22 Calocurb Study

26:02 Semaglutide vs Calocurb

29:45 Clinical trial results

32:54 Calocurb & PMS

34:10 Dosing Calocurb

40:08 Our personal experiences

43:37 Importance of protein intake

46:41 Females that are under-eating

54:52 Where to find Sarah & Calocurb

55:30 Her final piece of advice

57:21 Thanks for tuning in!

RESOURCES:

Website: www.Calocurb.com - Discount code: BIOHACKERBABES

IG: Calocurb

Facebook: CalocurbGLOBAL