#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why "Healthy Sedentary" Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyons
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Today, I'm joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a "healthy sedentary person" and reveals the major role of intramuscular fat in metabolic dysfunction.
Episode Timestamps:
Introduction, podcast focus, and welcoming Dr. Gabrielle Lyon ... 00:00:00
Muscle's impact on brain health, inflammation, and healthy aging ... 00:01:03
Dr. Lyon's childhood, grit, and self-discipline ... 00:04:33
Mentorship and protein science under Dr. Donald Lehman ... 00:07:05
Muscle as the overlooked metabolic organ ... 00:08:45
Why intramuscular fat matters more than body weight ... 00:10:06
Plant vs. animal protein for muscle health ... 00:13:29
Muscle as an endocrine organ and cognition ... 00:16:21
Future of muscle science: anabolics, imaging, and technology ... 00:18:22
GLP-1s, sarcopenic obesity, and muscle-first protocol ... 00:46:45
Sarcopenia, aging, and the importance of early training ... 01:04:35
Building lifelong resilience—mental and physical ... 01:08:31
Predictions: anabolics, muscle testing, and assessment ... 01:12:17
"Strength is a responsibility, not a luxury" ... 01:13:53
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